Improvement of personality functioning in patients with personality disorders: a comparative study of mentalization-based treatment versus non-manualized treatments - Scorecard - MDSpire

Improvement of personality functioning in patients with personality disorders: a comparative study of mentalization-based treatment versus non-manualized treatments

  • By

  • Kjetil Bremer

  • Geir Pedersen

  • Andreas Ekberg

  • Katharina T. E. Morken

  • Helene A. Nissen-Lie

  • Eileen Oftedal

  • Theresa Wilberg

  • Elfrida. H. Kvarstein

  • June 22, 2026

  • 0 min

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Clinical Scorecard: Enhancing Personality Functioning in Individuals with Personality Disorders: A Comparative Analysis of Mentalization-Based Treatment and Non-Manualized Approaches

At a Glance

CategoryDetail
ConditionPersonality Disorders
Key MechanismsMentalization-based treatment (MBT) aims to enhance mentalizing capacities; non-manualized treatments (NMT) vary in approach.
Target PopulationIndividuals with personality disorders, particularly those with Borderline PD and varying severity of personality pathology.
Care SettingOutpatient mental health services in Norway.

Key Highlights

  • MBT patients exhibited more severe personality pathology and higher symptom burden than NMT patients.
  • Both MBT and NMT showed clinically relevant improvements in personality functioning.
  • Improvement rates were larger in MBT for patients with Borderline PD and comorbid narcissistic traits.
  • Further development of effective treatments for avoidant PD is needed.

Guideline-Based Recommendations

Diagnosis

  • Utilize SCID-5-PD for baseline PD assessment.

Management

  • Implement MBT for patients with Borderline PD; consider NMT for other personality disorders.

Monitoring & Follow-up

  • Assess longitudinal changes in personality functioning using LPFS-BF and SIPP-SF.

Risks

  • Increased risk of substance use, self-harm, and suicidality associated with impaired personality functioning.

Patient & Prescribing Data

Patients with varying types of personality disorders receiving either MBT or NMT.

MBT is more effective for patients with severe personality disorders and specific traits like narcissism.

Clinical Best Practices

  • Admit patients to treatment based on severity and type of personality disorder.
  • Regular supervision and structured frameworks are essential in manualized treatments.

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