A prediction model and risk stratification tool for survival by chemotherapy in invasive micropapillary carcinoma of the breast: a population-based study with external validation - Scorecard - MDSpire

A prediction model and risk stratification tool for survival by chemotherapy in invasive micropapillary carcinoma of the breast: a population-based study with external validation

  • By

  • Fang Yang

  • Yiqi Yang

  • Qiuping Xu

  • Lin Tang

  • Yucai Wang

  • Elizabeth J. Cathcart-Rake

  • Li Xie

  • June 4, 2026

  • 0 min

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Clinical Scorecard: Development of a Survival Prediction Model and Risk Assessment Tool for Chemotherapy in Invasive Micropapillary Carcinoma of the Breast: Insights from a Population-Based Study with External Validation

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationFemale patients aged ≥18 years with histologically confirmed IMPC, excluding those with distant metastasis.
Care Setting

Key Highlights

  • Risk model developed to stratify patients based on marital status, tumor size, subtype, and radiotherapy history, aiding in personalized treatment decisions.

Guideline-Based Recommendations

Diagnosis

    Management

    • Consider chemotherapy primarily for high-risk IMPC patients, assessing clinical factors such as tumor grade and receptor status.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Chemotherapy improves OS in high-risk patients but not in low-risk patients; consider potential side effects.

        Clinical Best Practices

        • Utilize a risk stratification model for treatment decisions.
        • Incorporate patient marital status, tumor size, subtype, and radiotherapy history in assessments.
        • Recommend follow-up care to monitor for recurrence and manage side effects.

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