Neurodevelopmental trajectories from birth to childhood and their impairments: insights from passive, spontaneous, and locomotor-like movements - Scorecard - MDSpire

Neurodevelopmental trajectories from birth to childhood and their impairments: insights from passive, spontaneous, and locomotor-like movements

  • By

  • Damiana Rubeca

  • Francesca Sylos-Labini

  • Irina A. Solopova

  • Camilla Gizzi

  • Ambrogio Di Paolo

  • Arthur Dewolf

  • Yury Ivanenko

  • Francesco Lacquaniti

  • June 8, 2026

  • 0 min

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Clinical Scorecard: Developmental Pathways of Motor Skills from Infancy to Early Childhood and Associated Challenges: Perspectives from Involuntary, Natural, and Locomotive Movements

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationInfants and young children, particularly high-risk populations such as preterm infants, emphasizing the need for careful monitoring.
Care Setting

Key Highlights

  • Human motor behaviour evolves from prenatal to postnatal stages, reflecting CNS maturation.
  • General Movements (GMs) serve as sensitive markers of neural integrity in infants.
  • The stepping reflex is an early indicator of subcortical locomotor circuitry.
  • Independent locomotion typically emerges between 10 and 15 months.
  • Quantitative assessment tools enhance the detection of motor impairments.
  • Sensory feedback plays a crucial role in refining motor skills.

Guideline-Based Recommendations

Diagnosis

    Management

    • Support early, individualized intervention strategies for at-risk infants, such as tailored physical therapy and family education.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Infants and young children, particularly those with risk factors for neuromotor disorders.

        Early detection of deviations in motor behaviour can predict later impairments.

        Clinical Best Practices

        • Integrate findings from motor assessments with neurophysiological data.
        • Monitor developmental milestones closely in high-risk populations.
        • Utilize a combination of observational and quantitative assessment methods, ensuring integration with neurophysiological data.

        Related Resources & Content

        Original Source(s)

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