Systemic immune-inflammation Index and blood pressure control are independent and interactive predictors of atrial fibrillation recurrence after ablation - Scorecard - MDSpire

Systemic immune-inflammation Index and blood pressure control are independent and interactive predictors of atrial fibrillation recurrence after ablation

  • By

  • Yuhang Wei

  • Chenxi Cao

  • Yunzhe Wang

  • Pengli Yang

  • Wenjing Zhang

  • Jiahong Shangguan

  • Xijia Wang

  • Jiaqi Gao

  • Wenzhe Zong

  • Gangqiong Liu

  • May 15, 2026

  • 0 min

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Clinical Scorecard: Independent and Interactive Roles of Systemic Immune-Inflammation Index and Blood Pressure Management in Predicting Atrial Fibrillation Recurrence Post-Ablation

At a Glance

CategoryDetail
ConditionAtrial Fibrillation Recurrence Post-Ablation
Key MechanismsSystemic Immune-Inflammation Index (SII) and Blood Pressure Control
Target PopulationHypertensive patients undergoing first-time radiofrequency catheter ablation
Care SettingCardiovascular Medicine Department, First Affiliated Hospital of Zhengzhou University

Key Highlights

  • First study to evaluate SII's predictive value for AF recurrence in hypertensive patients post-ablation.
  • Blood pressure control significantly modifies the SII–AF recurrence association.
  • High SII and poorly controlled BP lead to a > 4-fold increase in recurrence risk.
  • SII outperforms conventional markers like AF duration and left atrial volume.

Guideline-Based Recommendations

Diagnosis

  • Assess pre-ablation SII levels in hypertensive AF patients.

Management

  • Prioritize blood pressure control in hypertensive patients undergoing RFCA.

Monitoring & Follow-up

  • Regularly monitor SII and blood pressure post-ablation for recurrence risk.

Risks

  • Elevated SII and poor BP control significantly increase AF recurrence risk.

Patient & Prescribing Data

568 hypertensive patients with atrial fibrillation undergoing RFCA.

Combined assessment of SII and BP control can improve individualized risk stratification.

Clinical Best Practices

  • Incorporate SII measurement in pre-ablation evaluations.
  • Implement strategies for effective blood pressure management in AF patients.

Related Resources & Content

Original Source(s)

Systemic immune-inflammation Index and blood pressure control are independent and interactive predictors of atrial fibrillation recurrence after ablation

  • by Yuhang Wei, Chenxi Cao, Yunzhe Wang, Pengli Yang, Wenjing Zhang, Jiahong Shangguan, Xijia Wang, Jiaqi Gao, Wenzhe Zong, Gangqiong Liu

  • May 15, 2026

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