Latent profile analysis of emergency department presentation characteristics in patients with acute ischemic stroke

Category	Detail
Condition	Acute Ischemic Stroke (AIS)
Key Mechanisms	Emergency department presentation characteristics, including symptom recognition and decision-making times.
Target Population	Patients presenting with acute ischemic stroke.
Care Setting	Emergency department

Four latent profiles of emergency department presentation identified: rapid EMS-activated, delayed recognition-self-presentation, family involvement-cautious decision-making, and multiple barriers-delayed presentation.
Significant differences in age, education, residence, living alone status, comorbidities, and clinical outcomes among profiles.
Rapid decision-making-emergency transport group had the highest reperfusion therapy rate (63.77%) and favorable prognosis rate (72.46%).
Multiple barriers-delayed presentation group had the lowest reperfusion rate (7.55%) and highest poor prognosis rate (86.79%).
Latent profile membership independently predicts functional prognosis beyond traditional clinical confounders.

Utilize Latent Profile Analysis to identify patient presentation characteristics.

Implement stratified intervention strategies based on profile characteristics to reduce presentation delays.

Assess time from onset to presentation and stroke knowledge levels as indicators of prognosis.

Higher odds of poor prognosis associated with multiple barriers-delayed presentation profile.

220 AIS patients admitted to the hospital.

Timely reperfusion therapy is crucial; fewer than 22% arrive within 3 hours of symptom onset.

Clinical Scorecard: Profile Analysis of Emergency Department Presentation Traits in Acute Ischemic Stroke Patients