Digital Mental Health Treatment and Symptoms of Depression and Anxiety in Breast Cancer Survivors: A - Scorecard - MDSpire

Exploring Digital Mental Health Interventions for Depression and Anxiety Symptoms in Survivors of Breast Cancer

  • By

  • Philip I. Chow

  • Wen You

  • Kelly M. Shaffer

  • Wendy F. Cohn

  • Shayna L. Showalter

  • Cynthia Orange

  • Lee M. Ritterband

  • David C. Mohr

  • July 20, 2026

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Clinical Scorecard: Exploring Digital Mental Health Interventions for Depression and Anxiety Symptoms in Survivors of Breast Cancer

At a Glance

CategoryDetail
ConditionDepression and Anxiety in Breast Cancer Survivors
Key MechanismsDigital mental health treatments (DMHTs) promote skills acquisition and reduce barriers to care.
Target PopulationWomen diagnosed with breast cancer (stages I-III) within the past 5 years.
Care SettingClinical trial evaluating digital mental health interventions.

Key Highlights

  • Nearly half of breast cancer survivors report significant depression or anxiety symptoms.
  • Digital mental health treatments can improve access to care for breast cancer survivors.
  • The IntelliCare program targets specific clinical concerns through brief interactions.
  • Sustained engagement in digital interventions is critical for efficacy.
  • Coaching may enhance engagement for users with initial difficulties.

Guideline-Based Recommendations

Diagnosis

  • Screen for depression using the PHQ-8 and anxiety using the GAD-7.

Management

  • Implement digital mental health treatments to address symptoms of depression and anxiety.

Monitoring & Follow-up

  • Assess engagement and symptom reduction at 8-week, 6-month, and 12-month follow-ups.

Risks

  • Exclude individuals with severe mental health conditions or unstable psychotropic medication.

Patient & Prescribing Data

Women aged 18 years or older with a recent breast cancer diagnosis.

DMHTs are scalable and can be accessed via smartphones, addressing barriers to traditional therapy.

Clinical Best Practices

  • Utilize digital tools to enhance mental health support for breast cancer survivors.
  • Monitor patient engagement to optimize treatment outcomes.
  • Consider adaptive coaching strategies for users with low initial engagement.

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