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Video: The Ultimate in Translational Medicine – with Harold Keer
Power List 2026 honoree Harold Keer traces oncology’s transformation – and considers what it will take to turn today’s “abundance of riches” into better patient outcomes
Clinical Scorecard: Video: The Ultimate in Translational Medicine – with Harold Keer
At a Glance
Category
Detail
Condition
Clinical topic addressed by the source article: Video
Key Mechanisms
The interview discusses the expansion of cancer treatments from cytotoxic chemotherapy to targeted therapies, monoclonal antibodies, immunotherapies, bispecific antibodies, and antibody-drug conjugates, as well as development efforts involving targets such as RAS.
Target Population
Patients or participants described in the source article.
Care Setting
Care setting described in the source article.
Key Highlights
Harold Keer describes industry as a route for scaling individual discoveries into medicines for patients.
Cancer drug development now includes targeted therapies, immunotherapies, bispecific antibodies, and antibody-drug conjugates alongside cytotoxic chemotherapy.
RAS, once considered an undruggable target, is now an active area of development.
The article discusses why promising cancer programs fail and the potential, as well as possible irrational exuberance, surrounding emerging modalities.
Keer emphasizes keeping patients at the center of clinical development and describes helping Taiho’s acquired ADC technology reach the clinic as unfinished work.
Guideline-Based Recommendations
Diagnosis
Management
Monitoring & Follow-up
Risks
Patient & Prescribing Data
The article discusses cancer patients broadly and provides no specific eligibility criteria or subgroup data.
It describes treatment modalities and drug-development challenges but provides no prescribing instructions, dosing, or comparative efficacy data.
Clinical Best Practices
Keer emphasizes keeping patients at the center of clinical development.
The interview describes destroying malignant cells while sparing healthy tissue as a fundamental challenge in cancer treatment.