Clinical Scorecard: The Relationship Between Physical Function and Psychosocial Outcomes Reported by Patients with Systemic Lupus Erythematosus

At a Glance

Key Highlights

• Approximately 30% of individuals with SLE are considered frail.
• Over half of individuals with SLE have poor physical performance.
• Psychosocial factors are robustly associated with physical function in SLE.
• Patient-reported outcomes (PROMs) are valuable for assessing patient experiences.
• Physical activity and structured exercise are recommended to improve patient outcomes.

Guideline-Based Recommendations

Diagnosis

• Diagnosis of SLE requires meeting four or more revised ACR criteria or three ACR criteria plus a diagnosis by a board-certified rheumatologist.

Management

• Incorporate patient-reported outcomes into clinical practice for holistic assessment.

Monitoring & Follow-up

• Regular assessment of physical function and psychosocial factors using validated instruments.

Risks

• Higher disease activity and comorbidities such as depression can exacerbate functional decline.

Patient & Prescribing Data

Adults (≥18 years) with SLE from diverse sociodemographic backgrounds.

Nonpharmacological interventions targeting psychosocial factors may improve daily functioning and quality of life.

Clinical Best Practices

• Utilize PROMIS Physical Function assessments for evaluating physical function.
• Assess fatigue and depression using validated scales to inform treatment strategies.
• Encourage physical activity as part of the management plan for SLE.

Related Resources & Content

• Systemic Lupus Erythematosus Questionnaire (SLAQ)
• Patient-Reported Outcomes Measurement Information System (PROMIS)