Comparative efficacy of early exercise interventions for recovery outcomes after total knee arthroplasty: a systematic review and network meta-analysis - Scorecard - MDSpire

Comparative efficacy of early exercise interventions for recovery outcomes after total knee arthroplasty: a systematic review and network meta-analysis

  • By

  • Xinyue Yan

  • PinMei Li

  • Jia Li

  • Liting Song

  • Jiapeng Jing

  • Xiaochen Fu

  • Zhuo Xu

  • July 17, 2026

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Clinical Scorecard: Effectiveness of Early Exercise Regimens on Recovery Following Total Knee Arthroplasty: A Systematic Review and Network Meta-Analysis

At a Glance

CategoryDetail
ConditionTotal Knee Arthroplasty Recovery
Key MechanismsEarly rehabilitation, exercise interventions, pain relief, functional recovery
Target PopulationPatients undergoing total knee arthroplasty
Care SettingPostoperative rehabilitation

Key Highlights

  • Functional training and resistance training showed favorable effects on pain relief.
  • Intelligence-assisted training demonstrated potential benefits across pain, functional status, and range of motion.
  • Early rehabilitation within 3 days post-surgery is crucial for optimizing outcomes.
  • Moderate evidence certainty for pain relief; low for functional status and range of motion.
  • A total of 32 RCTs involving 1,871 patients were analyzed.

Guideline-Based Recommendations

Diagnosis

    Management

    • Tailor exercise interventions based on rehabilitation stage and goals.

    Monitoring & Follow-up

      Risks

      • Persistent postoperative pain, functional limitations, and impaired proprioception.

      Patient & Prescribing Data

      Patients recovering from total knee arthroplasty

      Early exercise interventions initiated within 3 days post-surgery are essential for recovery.

      Clinical Best Practices

      • Implement functional training and resistance training as part of early rehabilitation.
      • Consider intelligence-assisted training to enhance rehabilitation outcomes.

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