Trajectories of symptom scores and risk of cardiovascular events in the vulnerable phase of heart failure: an analysis using a latent class trajectory model - Scorecard - MDSpire
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Symptom Score Patterns and Cardiovascular Event Risk During the Vulnerable Phase Post-Heart Failure Discharge: Insights from a Latent Class Trajectory Analysis
Clinical Scorecard: Symptom Score Patterns and Cardiovascular Event Risk During the Vulnerable Phase Post-Heart Failure Discharge: Insights from a Latent Class Trajectory Analysis
At a Glance
Category
Detail
Condition
Heart Failure
Key Mechanisms
Symptom trajectories post-discharge associated with cardiovascular outcomes.
Target Population
Patients with chronic heart failure post-hospitalization.
Care Setting
Tertiary hospital in Nanchang, China.
Key Highlights
18.7% of patients experienced major adverse cardiovascular events (MACEs) during follow-up.
Four distinct symptom trajectory groups identified: persistently declining, slowly improving, stable-moderate, and stable-high.
Persistently declining symptoms associated with higher odds of MACEs (OR = 2.242).
Tracking KCCQ trajectories may support early risk stratification.
Guideline-Based Recommendations
Diagnosis
Diagnosis of acute exacerbation of chronic HF according to the 2016 ESC Heart Failure Guidelines.
Management
Individualized management based on symptom trajectory patterns.
Monitoring & Follow-up
Longitudinal follow-up of symptoms using KCCQ at multiple time points.
Risks
High risks of rehospitalization and death during the vulnerable phase post-discharge.
Patient & Prescribing Data
1,109 patients with chronic heart failure.
Symptom recovery is heterogeneous; monitoring is crucial for risk stratification.
Clinical Best Practices
Utilize latent class trajectory modeling for symptom assessment.
Conduct follow-up assessments at multiple time points post-discharge.
Advanced heart failure and transplant cardiologist Sanjeev Kumar Gulati, M.D., FACC, has joined Baptist Health Heart & Vascular Care, and will serve as executive deputy director and system chief of cardiovascular medicine
