Systematic review and meta-analysis of digital interventions for mental health in cancer patients and survivors - Scorecard - MDSpire

Systematic review and meta-analysis of digital interventions for mental health in cancer patients and survivors

  • By

  • Zekariyas Sahile Nezenega

  • Setognal B. Aychiluhm

  • Allen G. Ross

  • Zemenu Yohannes Kassa

  • Meless G. Bore

  • Cheru Tesema Leshargie

  • Julaine Allan

  • Subash Thapa

  • Feleke Hailemichael Astawesegn

  • Shakeel Mahmood

  • Vivian Isaac

  • Abel F. Dadi

  • Birhanu W. Demissie

  • Fentaw T. Berhe

  • Engida Yisma

  • Werissaw Haileselassie

  • Teketo K. Tegegne

  • Kedir Y. Ahmed

  • December 27, 2025

  • 0 min

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Clinical Scorecard: Comprehensive Review and Meta-Analysis of Digital Health Solutions for Mental Well-Being in Cancer Patients and Survivors

At a Glance

CategoryDetail
ConditionMental health conditions including anxiety, depression, psychological distress, insomnia, and sleep disturbances in cancer patients and survivors
Key MechanismsDigital health interventions (DHIs) such as social media-based platforms, mHealth, telehealth, virtual reality, and web-based solutions provide psychological support, symptom monitoring, and self-management resources
Target PopulationCancer patients and survivors experiencing mental health challenges
Care SettingOutpatient and community settings utilizing digital platforms for mental health support

Key Highlights

  • Meta-analysis of 139 randomized controlled trials involving 19,233 participants across 25 countries
  • DHIs significantly reduce anxiety, depression, psychological distress, insomnia, and improve sleep quality in cancer populations
  • Social media-based, mHealth, telehealth, virtual reality, and combined web-based interventions show moderate to low certainty evidence of effectiveness

Guideline-Based Recommendations

Diagnosis

  • Assess mental health conditions including anxiety, depression, psychological distress, and sleep disturbances in cancer patients and survivors

Management

  • Implement digital health interventions such as social media-based programs, mHealth apps, telehealth services, virtual reality, and web-based platforms to support mental well-being
  • Combine web-based interventions with telehealth for enhanced benefits

Monitoring & Follow-up

  • Regularly monitor mental health outcomes using validated scales to evaluate intervention effectiveness
  • Track adherence and engagement with digital health tools

Risks

  • Consider variability in evidence certainty across intervention types
  • Be aware of potential access disparities due to digital literacy or resource availability

Patient & Prescribing Data

Cancer patients and survivors experiencing mental health symptoms

Digital health interventions provide accessible, affordable, and scalable mental health support, effectively reducing anxiety, depression, psychological distress, and improving sleep-related outcomes

Clinical Best Practices

  • Incorporate digital health interventions as adjuncts or alternatives to conventional face-to-face mental health support
  • Tailor intervention modality to patient preference and resource availability
  • Address barriers such as stigma, access to specialists, and cost through digital solutions
  • Use evidence-based digital platforms with demonstrated efficacy in cancer populations

References

Original Source(s)

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