A targeted behavioral economics-based mobile health intervention to improve medication adherence in patients with hypertension: A three-arm randomized controlled trial - Scorecard - MDSpire
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A Mobile Health Intervention Utilizing Behavioral Economics to Enhance Medication Adherence in Hypertensive Patients: Results from a Three-Arm Randomized Controlled Trial

  • By

  • Jan Strebel

  • Anjali Raja Beharelle

  • Michael Mayr

  • Valeriya Nemtsova

  • Joachim Zahnd

  • Gregoire Wuerzner

  • Georg Ehret

  • Michael Stiefel

  • Emrush Rexhaj

  • Théo Meister

  • Annina S. Vischer

  • Thilo Burkard

  • August 29, 2026

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Clinical Scorecard: A Mobile Health Intervention Utilizing Behavioral Economics to Enhance Medication Adherence in Hypertensive Patients: Results from a Three-Arm Randomized Controlled Trial

At a Glance

CategoryDetail
ConditionHypertension
Key MechanismsUtilization of a mobile health application to enhance medication adherence through reminders, financial incentives, and positive reinforcement.
Target PopulationHypertensive outpatients in Switzerland.
Care SettingTertiary-care hospital centers.

Key Highlights

  • Non-adherence rates among hypertensive patients range from 50% to 80%.
  • The study evaluated a mobile application designed to improve medication adherence.
  • Participants were randomized into three groups: mApp with financial incentives, mApp without incentives, and standard-of-care.
  • The mApp includes features like medication reminders and gamification to support adherence.
  • The study was conducted across five urban tertiary-care centers in Switzerland.

Guideline-Based Recommendations

Diagnosis

  • Regular monitoring of blood pressure as per the 2018 ESC/ESH guidelines.

Management

  • Utilization of multifaceted interventions to improve medication adherence.

Monitoring & Follow-up

  • Assessment of adherence and blood pressure at baseline, endpoint, and during follow-up.

Risks

  • Non-adherence contributes to increased mortality and healthcare costs.

Patient & Prescribing Data

Hypertensive patients experiencing non-adherence to medication.

Financial incentives may enhance adherence rates among patients using the mApp.

Clinical Best Practices

  • Implement reminder systems and patient education to improve adherence.
  • Consider financial incentives as part of adherence interventions.

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