Mailed Outreach for Colorectal Cancer Screening in Community Health Centers: The CARES Pragmatic Cluster - Scorecard - MDSpire

Mailed Outreach for Colorectal Cancer Screening in Community Health Centers: The CARES Pragmatic Cluster

  • By

  • Folasade P. May

  • Suzanne Brodney

  • Jessica J. Tuan

  • Sapna Syngal

  • Andrew T. Chan

  • Beth Glenn

  • Gina Johnson

  • Yuchiao Chang

  • David A. Drew

  • Beverly Moy

  • Nicolette J. Rodriguez

  • Erica T. Warner

  • Adjoa Anyane-Yeboa

  • Chinedu Ukaegbu

  • Anjelica Q. Davis

  • Kimberly Schoolcraft

  • Susan Regan

  • Kelley Le Beaux

  • Ellen T. Lee

  • Roopa Bhat

  • Alexis Gordon

  • Linh K. Phan

  • Andrea Fernanda Cortés Chirino

  • Caylin J. Marotta

  • Rachel G. Z. Kindermann

  • Jennifer S. Haas

  • June 1, 2026

  • 0 min

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Clinical Scorecard: Postal Outreach for Colorectal Cancer Screening in Community Health Clinics: Insights from the CARES Pragmatic Study

At a Glance

CategoryDetail
ConditionColorectal Cancer (CRC)
Key MechanismsStool-based screening tests (FIT and FIT-DNA) to increase screening uptake.
Target PopulationIndividuals aged 45 to 75 years, due for CRC screening, receiving care from community health clinics.
Care SettingCommunity Health Clinics (CHCs)

Key Highlights

  • CRC is the second most common cause of cancer mortality in the US.
  • Mailed outreach significantly increased CRC screening participation (30.0% vs 9.7%).
  • FIT-DNA offers higher sensitivity and a manufacturer-administered patient assistance program.

Guideline-Based Recommendations

Diagnosis

  • Eligibility includes individuals aged 45-75, due for CRC screening, and no prior CRC documentation.

Management

  • Follow-up colonoscopy is required for abnormal results from stool tests.

Monitoring & Follow-up

  • Screening participation is tracked within 90 days of test mailing.

Risks

  • Low follow-up care rates for patients needing colonoscopy after abnormal results.

Patient & Prescribing Data

Patients in underresourced settings receiving care at CHCs.

Stool-based tests (FIT and FIT-DNA) are primary screening modalities.

Clinical Best Practices

  • Utilize mailed outreach and automated reminders to increase screening uptake.
  • Ensure cultural appropriateness in outreach materials.

Related Resources & Content

Original Source(s)

Mailed Outreach for Colorectal Cancer Screening in Community Health Centers: The CARES Pragmatic Cluster

  • by Folasade P. May, Suzanne Brodney, Jessica J. Tuan, Sapna Syngal, Andrew T. Chan, Beth Glenn, Gina Johnson, Yuchiao Chang, David A. Drew, Beverly Moy, Nicolette J. Rodriguez, Erica T. Warner, Adjoa Anyane-Yeboa, Chinedu Ukaegbu, Anjelica Q. Davis, Kimberly Schoolcraft, Susan Regan, Kelley Le Beaux, Ellen T. Lee, Roopa Bhat, Alexis Gordon, Linh K. Phan, Andrea Fernanda Cortés Chirino, Caylin J. Marotta, Rachel G. Z. Kindermann, Jennifer S. Haas

  • June 1, 2026

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