Patient Awareness, Attitudes, and Preventive Practices Related to Venous Thromboembolism in Multiple Myeloma: A Cross-Sectional Analysis - Scorecard - MDSpire
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Patient Awareness, Attitudes, and Preventive Practices Related to Venous Thromboembolism in Multiple Myeloma: A Cross-Sectional Analysis
Clinical Scorecard: Patient Awareness, Attitudes, and Preventive Practices Related to Venous Thromboembolism in Multiple Myeloma: A Cross-Sectional Analysis
At a Glance
Category
Detail
Condition
Venous thromboembolism (VTE) in multiple myeloma (MM) patients
Key Mechanisms
Hypercoagulable state induced by MM and treatment-related factors, especially immunomodulators and chemotherapy
Target Population
Patients diagnosed with multiple myeloma undergoing treatment
Care Setting
Hospital-based hematology/oncology care, specifically Bazhong Central Hospital
Key Highlights
MM patients have a ninefold increased risk of VTE compared to the general population, with most events occurring within six months of treatment initiation.
Patient knowledge and attitudes toward VTE prevention are suboptimal despite some proactive preventive practices.
Knowledge positively influences attitudes, which in turn strongly affect preventive practices, highlighting the importance of patient education.
Guideline-Based Recommendations
Diagnosis
Early thrombotic risk assessment is critical for all MM patients starting anti-myeloma therapy.
Management
Use of prophylactic anticoagulants such as low-molecular-weight heparin, warfarin, or direct oral anticoagulants tailored to individual risk.
Repeated risk reassessment throughout the chronic, relapsing disease course to adjust thromboprophylaxis accordingly.
Risks
High VTE risk driven by MM disease biology and treatment, especially immunomodulatory agents combined with high-dose dexamethasone.
Suboptimal patient adherence to VTE prevention strategies can increase morbidity and mortality.
Patient & Prescribing Data
504 MM patients surveyed at Bazhong Central Hospital, majority male (65.1%), with 57.7% reporting prior VTE.
Despite proactive preventive practices, knowledge and attitudes remain insufficient, suggesting a need for enhanced patient education to improve adherence and outcomes.
Clinical Best Practices
Implement targeted patient education programs to improve VTE knowledge and attitudes in MM patients.
Incorporate KAP assessments into routine care to identify gaps and tailor prevention strategies.
Engage family members or caregivers to support elderly or cognitively impaired patients in understanding and adhering to VTE prevention.
Prioritize early and ongoing thrombotic risk assessment aligned with treatment phases.
Customize anticoagulant prophylaxis based on individual patient risk profiles and preferences.
