Risk factors for hospital readmission in chronic obstructive pulmonary disease: a systematic review and meta-analysis - Scorecard - MDSpire

Risk factors for hospital readmission in chronic obstructive pulmonary disease: a systematic review and meta-analysis

  • By

  • Hao Tian

  • Wei Shen

  • Liuyang Huang

  • Bowen Feng

  • Baoyue Hong

  • Xianzheng Li

  • Fanrong Liang

  • Chunyan Yang

  • Qingguang Qin

  • July 14, 2026

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Clinical Scorecard: Identifying Factors Associated with Hospital Readmission in Patients with Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis

At a Glance

CategoryDetail
ConditionChronic Obstructive Pulmonary Disease (COPD)
Key MechanismsAcute exacerbations leading to hospitalization and potential readmissions.
Target PopulationPatients with COPD, particularly older adults.
Care SettingHospital and post-discharge management.

Key Highlights

  • Pooled readmission rates: 15.2% within 1 month, 26.9% within 3 months, 30.4% within 6 months, and 42.1% within 1 year.
  • Identified 26 factors associated with readmission.
  • Readmission is a significant predictor of increased mortality risk.
  • GOLD guidelines recommend a multidimensional approach for COPD assessment.
  • Frequent exacerbations are linked to worsening health and increased healthcare costs.

Guideline-Based Recommendations

Diagnosis

  • Assess exacerbation history over the preceding 12 months for risk stratification.

Management

  • Tailor management strategies for patients with two or more acute exacerbations within 1 year or at least one requiring hospitalization.

Monitoring & Follow-up

  • Monitor readmission rates as a clinically meaningful outcome for evaluating COPD prognosis.

Risks

  • Readmissions indicate disease instability and are associated with poorer quality of life and higher economic burden.

Patient & Prescribing Data

Patients hospitalized for acute exacerbations of COPD.

Early identification of high-risk patients is crucial for targeted interventions.

Clinical Best Practices

  • Implement strategies to reduce avoidable readmissions.
  • Utilize a multidimensional approach for COPD assessment as per GOLD guidelines.
  • Focus on early recognition of high-risk patients for timely interventions.

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