Application of transvaginal color doppler ultrasound in early diagnosis of threatened abortion and its correlation with serum levels of β - hCG and CA125 - Scorecard - MDSpire
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Application of transvaginal color doppler ultrasound in early diagnosis of threatened abortion and its correlation with serum levels of β - hCG and CA125
Clinical Scorecard: Utilization of Transvaginal Color Doppler Ultrasound for Early Detection of Threatened Abortion and Its Relationship with Serum β-hCG and CA125 Levels
At a Glance
Category
Detail
Condition
Threatened Abortion
Key Mechanisms
Transvaginal color Doppler ultrasound, serum β-HCG, and CA125 levels
Target Population
Pregnant women with threatened abortion
Care Setting
Obstetrics and Gynecology
Key Highlights
TVCDS has 92.86% sensitivity and 100% specificity for diagnosing threatened abortion.
Higher corpus luteum PI and RI, and lower β-HCG levels were observed in the observation group.
Combined predictive model using PI, β-HCG, and CA125 yielded an AUC of 0.931.
Guideline-Based Recommendations
Diagnosis
Diagnosis of threatened abortion should be based on clinical criteria and supported by ultrasound findings.
Management
Consider the use of TVCDS and serum markers for risk assessment in threatened abortion.
Monitoring & Follow-up
Monitor serum β-HCG and CA125 levels alongside ultrasound findings.
Risks
Indiscriminate pregnancy preservation may increase financial and psychological burdens.
Patient & Prescribing Data
Primiparous women with a single pregnancy at 6–8 weeks of gestation.
No prior treatment with progesterone or HCG for pregnancy preservation before admission.
Clinical Best Practices
Utilize TVCDS as an adjunctive tool for assessing embryonic viability.
Evaluate corpus luteum blood flow parameters in conjunction with serum indicators.
