Association of serum 25-hydroxyvitamin D levels with indicators of target organ damage in patients with diabetes: a cross-sectional study - Scorecard - MDSpire

Association of serum 25-hydroxyvitamin D levels with indicators of target organ damage in patients with diabetes: a cross-sectional study

  • By

  • Min Wang

  • Yanrong Huang

  • Yilun Gong

  • Lina Li

  • Zhenxing Zeng

  • Chuanfang Jiang

  • Guozhong Ji

  • June 29, 2026

  • 0 min

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Clinical Scorecard: Relationship Between Serum 25-Hydroxyvitamin D Concentrations and Target Organ Damage Markers in Diabetic Patients: A Cross-Sectional Analysis

At a Glance

CategoryDetail
ConditionDiabetes-related target organ damage
Key MechanismsAssociation of serum 25-hydroxyvitamin D levels with peripheral nerve dysfunction, carotid plaque, and urinary microalbumin.
Target PopulationAdults with type 1 or type 2 diabetes mellitus
Care SettingDepartment of Endocrinology, Jen Ching Memorial Hospital

Key Highlights

  • Lower serum 25(OH)D levels are associated with peripheral nerve damage and carotid plaque.
  • Inversely associated with urinary microalbumin levels.
  • Higher serum 25(OH)D linked to lower odds of cerebral infarction and coronary heart disease.

Guideline-Based Recommendations

Diagnosis

  • Assess serum 25(OH)D levels in diabetic patients to evaluate risk of target organ damage.

Management

  • Consider monitoring vitamin D levels as part of diabetes management.

Monitoring & Follow-up

  • Regular assessment of serum 25(OH)D in patients with diabetes.

Risks

  • Vitamin D deficiency may increase the risk of diabetic complications.

Patient & Prescribing Data

372 adults with diabetes

Vitamin D status may influence the risk of complications in diabetes.

Clinical Best Practices

  • Incorporate vitamin D level assessment in routine diabetes care.
  • Educate patients on the importance of maintaining adequate vitamin D levels.

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