Metabolic and bariatric surgery in mild obesity: mid-term outcomes and safety in an Asian population
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By
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Wanying Zhong
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Lijun Chen
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Yuanhao Huang
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Dalong Zhu
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Wenjuan Tang
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Yuqin Ouyang
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Xuehui Chu
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Wenhuan Feng
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May 20, 2026
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Clinical Scorecard: Outcomes and Safety of Metabolic and Bariatric Surgery for Mild Obesity in an Asian Cohort: A Mid-Term Analysis
At a Glance
| Category | Detail |
|---|
| Condition | |
| Key Mechanisms | |
| Target Population | Asian patients with mild obesity (BMI 27.5-32.5 kg/m²) and those with higher BMI (≥32.5 kg/m²). |
| Care Setting | |
Key Highlights
- MBS in mild obesity group resulted in lower %TWL (20% vs 26%) compared to higher BMI group; consider discussing clinical significance.
- Comparable rates of achieving composite metabolic endpoints (30.7% vs 27.6%) warrant further explanation.
Guideline-Based Recommendations
Diagnosis
Management
- Consider MBS for patients with BMI 27.5-32.5 kg/m² and multiple metabolic risk factors; specify types of risk factors.
Monitoring & Follow-up
Risks
Patient & Prescribing Data
MBS provides durable metabolic benefits despite lower weight loss in mild obesity; discuss potential risks.
Clinical Best Practices
- Prioritize early intervention for mild obesity to prevent progression to metabolic diseases; support with evidence.
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