Comparison of Opioid-Free Versions of Total Intravenous Anesthesia and Inhalational Anesthesia in Bariatric Surgery: A Randomized Controlled Trial - Scorecard - MDSpire

Evaluation of Opioid-Free Total Intravenous Anesthesia Versus Inhalational Anesthesia in Bariatric Surgical Procedures: A Randomized Controlled Study

  • By

  • Pawel Maciejewski

  • Tomasz Skladzien

  • Michal Cicio

  • Lukasz Tabin

  • Tomasz Lonc

  • Olga Szkudlarek

  • Tomasz Klimczyk

  • Anna Kwinta

  • Aleksandra Zmuda

  • Tomasz Drygalski

  • Piotr Major

  • Michal Terlecki

  • July 20, 2026

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Clinical Scorecard: Evaluation of Opioid-Free Total Intravenous Anesthesia Versus Inhalational Anesthesia in Bariatric Surgical Procedures: A Randomized Controlled Study

At a Glance

CategoryDetail
ConditionObesity
Key MechanismsOpioid-free anesthesia techniques to reduce postoperative opioid consumption and improve recovery profiles.
Target PopulationAdult patients (≥ 18 years) with severe obesity (BMI ≥ 35 kg/m²) scheduled for laparoscopic sleeve gastrectomy.
Care SettingTertiary University Hospital

Key Highlights

  • Comparison of opioid-free TIVA with propofol versus inhalational anesthesia with sevoflurane.
  • Focus on postoperative nausea and vomiting (PONV) incidence within 24 hours after surgery.
  • Inclusion of multimodal analgesia and opioid-sparing techniques in anesthetic management.

Guideline-Based Recommendations

Diagnosis

  • Patients should be screened for eligibility based on BMI and ASA physical status.

Management

  • Utilize opioid-free anesthesia techniques to minimize opioid use and related complications.

Monitoring & Follow-up

  • Standard monitors including ECG, blood pressure, pulse oximetry, and depth of anesthesia should be applied.

Risks

  • Increased sensitivity to opioids and risk of respiratory depression in bariatric patients.

Patient & Prescribing Data

Adult patients with severe obesity undergoing elective laparoscopic sleeve gastrectomy.

Incorporation of agents like lidocaine, ketamine, and dexmedetomidine in opioid-free anesthesia protocols.

Clinical Best Practices

  • Implement Enhanced Recovery After Surgery protocols emphasizing early mobilization.
  • Consider multimodal analgesia to improve patient outcomes.

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