Physical exercise in brain tumor patients: a systematic review - Scorecard - MDSpire
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Exercise Interventions for Patients with Brain Tumors: A Comprehensive Review

  • By

  • Arooba Iqbal

  • L. Nicolas Gonzalez Castro

  • September 7, 2026

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Clinical Scorecard: Exercise Interventions for Patients with Brain Tumors: A Comprehensive Review

At a Glance

CategoryDetail
ConditionBrain Tumors
Key MechanismsExercise stimulates metabolic and signaling pathways, supporting mitochondrial biogenesis and enhancing metabolic regulation.
Target PopulationPatients with primary and metastatic brain tumors
Care SettingOncology

Key Highlights

  • Physical exercise is feasible and generally safe for brain tumor patients.
  • Exercise interventions include aerobic, strength-training, yoga, and balance exercises.
  • Potential improvements in physical and cognitive function and quality of life were noted.
  • Adverse events related to exercise were uncommon and similar to those in non-cancer populations.
  • The evidence regarding clinical effectiveness remains preliminary and requires further research.

Guideline-Based Recommendations

Diagnosis

    Management

    • Exercise guidelines for cancer survivors exist but are not tailored specifically for brain tumor patients.

    Monitoring & Follow-up

      Risks

      • High risk of bias in studies and small sample sizes limit the applicability of findings.

      Patient & Prescribing Data

      Individuals diagnosed with brain tumors

      Exercise may help manage symptoms and improve quality of life.

      Clinical Best Practices

      • Encourage participation in structured exercise interventions.
      • Monitor patients for adverse events during exercise.

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