Evaluating the Relationship Between Axial Length to Corneal Curvature Radius Ratio and Myopia in Pediatric Populations
By
Lin Wang
Qianru Zhang
Changdong Liu
Qiqi Liu
Peipei Zhang
April 21, 2026
Clinical Scorecard: Evaluating the Relationship Between Axial Length to Corneal Curvature Radius Ratio and Myopia in Pediatric Populations
At a Glance
Category Detail
Condition Myopia in children and adolescents Key Mechanisms Association of axial length to corneal curvature radius ratio (AL/CR) with myopia progression Target Population Children and adolescents aged 6 to 12 years Care Setting Optometry clinic
Key Highlights
AL/CR shows a stronger correlation with spherical equivalent than axial length in predicting myopia. The study included 2,760 eyes from children aged 6 to 12 years. AL/CR cutoff point for myopia detection is 3.026 with sensitivity of 0.898 and specificity of 0.826. Myopia prevalence in children is projected to rise significantly by 2050. Age of myopia onset is a critical predictor of high myopia risk. Guideline-Based Recommendations
Diagnosis
Use AL/CR ratio as a key parameter for diagnosing myopia. Define myopia as spherical equivalent (SE) ≤ −0.50 diopters (D). Management
Implement early detection strategies based on AL/CR measurements. Monitoring & Follow-up
Regularly assess ocular biometry and refractive parameters in children. Risks
Increased risk of high myopia associated with early onset of myopia. Patient & Prescribing Data
Children and adolescents aged 6 to 12 years without ocular diseases.
Focus on monitoring AL/CR for predicting myopia progression.
Clinical Best Practices
Conduct comprehensive ocular examinations including cycloplegic refraction. Utilize AL/CR as a predictive tool for myopia in pediatric populations. References
