Global Prevalence and Impact of Pediatric Gut-Brain Interaction Disorders: Findings from the Rome Foundation's International Study
By
Samuel Nurko
Tiffany Taft
Olafur S Palsson
Marc Benninga
Carlo DiLorenzo
Rachel Rosen
Miguel Saps
Johann P Hreinsson
Xiucai Fang
Mizu Jiang
Caterina Strisciuglio
Erick Toro-Monjaraz
Ami D Sperber
October 1, 2026
Clinical Scorecard: Global Prevalence and Impact of Pediatric Gut-Brain Interaction Disorders: Findings from the Rome Foundation's International Study
At a Glance
Category Detail
Condition Pediatric Disorders of Gut-Brain Interaction (DGBI) Key Mechanisms Defined by Rome V criteria, encompassing various gastrointestinal symptoms and disorders. Target Population Children aged 0-17 years across multiple countries. Care Setting Global epidemiological investigation.
Key Highlights
Almost one-third of children are affected by pediatric DGBI. Prevalence varies significantly by disorder and country. Conditions impose a substantial burden on children and caregivers. Study provides standardized worldwide prevalence estimates. First large-scale multinational investigation of pediatric DGBI. Guideline-Based Recommendations
Diagnosis
Utilize the Rome V paediatric diagnostic questionnaire for accurate classification. Management
Address psychosocial dysfunction and healthcare utilization associated with DGBI. Monitoring & Follow-up
Assess symptom severity and its impact on daily activities and quality of life. Risks
Consider the burden of DGBI on family dynamics and healthcare systems. Patient & Prescribing Data
Children aged 0-17 years with diagnosed DGBI.
Focus on managing symptoms and associated psychosocial factors.
Clinical Best Practices
Implement standardized diagnostic criteria for consistency in diagnosis. Incorporate caregiver feedback in assessing the impact of DGBI. Utilize validated instruments to measure DGBI burden and symptoms. Related Resources & Content
