Personalized Cancer Vaccine Linked to Three-Year Disease-Free Survival in Head and Neck Cancer
All 16 patients who received TG4050 after standard treatment remained disease-free, compared with 13 of 16 patients in the control group
Clinical Scorecard: Personalized Cancer Vaccine Linked to Three-Year Disease-Free Survival in Head and Neck Cancer
At a Glance
| Category | Detail |
| Condition | Clinical topic addressed by the source article: Personalized Cancer Vaccine Linked to Three-Year Disease-Free Survival in Head and Neck Cancer |
| Key Mechanisms | Mechanisms or clinical associations described in the source article. |
| Target Population | Population described in the source article. |
| Care Setting | Specify the type of oncology clinical trials (e.g., phase I, II). |
Key Highlights
- All 16 patients treated with TG4050 remained disease-free after a median follow-up of 41 months.
- Three of 16 patients in the control group experienced disease recurrence.
- The vaccine induced detectable T-cell responses in 73.3% of evaluated patients.
- Responses could be detected more than a year after the final dose.
- No unexpected safety findings were reported during long-term follow-up.
Guideline-Based Recommendations
Diagnosis
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Monitoring & Follow-up
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Patient & Prescribing Data
Detail how sequencing informs the vaccine design.
Clinical Best Practices
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