My risk perception; perspectives from youth at familial risk for bipolar disorder: a qualitative study - Scorecard - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Youth Perspectives on Risk Awareness Related to Familial Bipolar Disorder: A Qualitative Investigation

  • By

  • Yusef Ahmed

  • Freja Pind Pilegaard

  • Stine Pedersen

  • Maj Vinberg

  • Christina Wagner

  • December 16, 2025

Share

Clinical Scorecard: Youth Perspectives on Risk Awareness Related to Familial Bipolar Disorder: A Qualitative Investigation

At a Glance

CategoryDetail
ConditionBipolar Disorder (BD)
Key MechanismsHigh heritability with additional environmental factors; early onset before age 25; episodic mood shifts and behavioural changes
Target PopulationOffspring aged 15-25 of parents diagnosed with bipolar disorder
Care SettingMental health outpatient clinics and family-focused preventive interventions

Key Highlights

  • Offspring of parents with BD have up to eleven-fold increased risk of BD and higher rates of depression and anxiety.
  • Mood instability and high heritability create unique developmental challenges for at-risk youth.
  • Family communication and early intervention approaches like Family-Focused Therapy for High-Risk Youth (FFT-HR) show promise.

Guideline-Based Recommendations

Diagnosis

  • Recognize offspring of parents with BD as a high-risk group for early symptom emergence.
  • Use self-report screening instruments to assess mood and family dynamics; no systematic diagnostic interviews conducted in this study.

Management

  • Implement preventive and early intervention approaches tailored for youth at familial risk, such as FFT-HR.
  • Improve family communication to support earlier recognition of symptoms and timely help-seeking.

Monitoring & Follow-up

  • Monitor changes in sleep, energy, and mood regulation as early risk indicators.
  • Engage youth perspectives to refine and adapt preventive interventions.

Risks

  • Increased emotional distress, insecurity, role confusion, and caregiving responsibilities in offspring.
  • Stigma and silence within families may hinder help-seeking and increase internalizing symptoms.

Patient & Prescribing Data

Adolescents and young adults (15-25 years) with at least one parent diagnosed with BD

Preventive interventions focusing on family communication and coping strategies are preferred; youth perspectives are critical for tailoring support.

Clinical Best Practices

  • Ensure confidentiality and privacy when engaging offspring in research or clinical settings.
  • Use semi-structured interviews to explore offspring experiences and perceptions about familial BD risk.
  • Involve multidisciplinary teams including clinicians and individuals with lived experience for comprehensive analysis.
  • Apply qualitative content analysis with iterative coding and consensus to understand youth perspectives.
  • Incorporate youth feedback to develop developmentally appropriate and acceptable preventive interventions.

References

Original Source(s)

Related Content