Influence of Sex, Gender, and Sociodemographic Variables on Recurrent Prescription Refills for Chronic Pain: Findings from a Prescription Claims Analysis - Scorecard - MDSpire

Influence of Sex, Gender, and Sociodemographic Variables on Recurrent Prescription Refills for Chronic Pain: Findings from a Prescription Claims Analysis

  • By

  • Marimée Godbout-Parent

  • Nancy Julien

  • Hermine Lore Nguena Nguefack

  • M. Gabrielle Pagé

  • Line Guénette

  • Lucie Blais

  • Nancy Ménard

  • Sylvie Beaudoin

  • Anaïs Lacasse

  • April 22, 2026

  • 0 min

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Clinical Scorecard: Influence of Sex, Gender, and Sociodemographic Variables on Recurrent Prescription Refills for Chronic Pain: Findings from a Prescription Claims Analysis

At a Glance

CategoryDetail
ConditionChronic Pain
Key MechanismsInfluence of sex, gender identity, and sociodemographic factors on medication use and prescription refills.
Target PopulationIndividuals living with chronic pain, particularly women and gender-diverse individuals.
Care SettingCommunity pharmacies and healthcare systems in Quebec, Canada.

Key Highlights

  • Chronic pain affects up to one in four individuals worldwide.
  • Women and gender-diverse individuals show different patterns of medication use compared to men.
  • Antidepressants (48%) and anticonvulsants (35%) are the most commonly prescribed medications for chronic pain.
  • Statistically significant differences in prescription refills were noted among various sociodemographic subgroups.
  • The study emphasizes the need for an equity-oriented approach to chronic pain management.

Guideline-Based Recommendations

Diagnosis

  • Consider a multimodal treatment approach for chronic pain management.

Management

  • Pharmacological treatments should be weighed against potential benefits and risks for each patient.

Monitoring & Follow-up

  • Monitor prescription refill patterns to assess medication adherence and effectiveness.

Risks

  • Be aware of the side effects and challenges associated with polypharmacy in chronic pain treatment.

Patient & Prescribing Data

Individuals with chronic pain, including diverse gender identities and various sociodemographic backgrounds.

Medication use varies significantly by sex and gender, with implications for prescribing practices.

Clinical Best Practices

  • Utilize an intersectional health perspective in understanding medication use.
  • Incorporate sex and gender considerations into chronic pain management strategies.
  • Promote equitable access to effective treatments for all individuals with chronic pain.

References

Original Source(s)

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