Quality of Life and Its Influencing Factors in Patients with neuromyelitis optica spectrum disorder
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By
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Lei, Zhi-Yin
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Li, Hui-Ping
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Yang, Qing
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Zhang, Xiao-pei
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Wang, Li-xin
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Liu, Zhuyun
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June 4, 2026
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Clinical Scorecard: Factors Affecting Quality of Life in Individuals with Neuromyelitis Optica Spectrum Disorder
At a Glance
| Category | Detail |
|---|
| Condition | Clinical topic addressed by the source article: Factors Affecting Quality of Life in Individuals with Neuromyelitis Optica Spectrum Disorder |
| Key Mechanisms | Psychosocial factors including depressive symptoms, social avoidance, and sleep quality impact health-related quality of life. |
| Target Population | Patients or participants described in the source article. |
| Care Setting | Care setting described in the source article. |
Key Highlights
- 216 Chinese NMOSD patients evaluated for health-related quality of life.
- Significantly reduced median Physical Component Summary (PCS) and Mental Component Summary (MCS) scores.
- Older age, depressive symptoms, social avoidance, and poor sleep associated with worse PCS.
- Depressive symptoms, social avoidance, poor sleep quality, and lower resilience associated with worse MCS.
Guideline-Based Recommendations
Diagnosis
Management
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Chinese patients with NMOSD
Psychosocial factors critically influence health-related quality of life.
Clinical Best Practices
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