Outcomes and Visual Performance Following the Use of Mini-Monovision Extended Depth of Focus Intraocular Lenses - Scorecard - MDSpire
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Outcomes and Visual Performance Following the Use of Mini-Monovision Extended Depth of Focus Intraocular Lenses

  • By

  • Yubing Huang

  • Min Han

  • Zhuoqing Hu

  • Xinyi Zhang

  • Haokun Qu

  • Zheming Wu

  • Yun Chen

  • Weitao Zheng

  • Lina Wu

  • Ruihong Ju

  • December 25, 2025

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Clinical Scorecard: Outcomes and Visual Performance Following the Use of Mini-Monovision Extended Depth of Focus Intraocular Lenses

At a Glance

CategoryDetail
ConditionPresbyopia and cataract in elderly patients with myopia
Key MechanismsExtended depth-of-focus (EDOF) intraocular lenses (IOLs) using wavefront-shaping technology to elongate focal range; mini-monovision strategy inducing slight anisometropia (<1.00 D) to enhance near vision
Target PopulationAdults aged ≥18 years undergoing bilateral cataract surgery with Vivity EDOF IOL implantation
Care SettingOphthalmology surgical and postoperative outpatient care

Key Highlights

  • Mini-monovision with Vivity EDOF IOL involves targeting emmetropia in dominant eye and mild myopia (0.5–1.0 D) in non-dominant eye to improve near vision.
  • Anisometropia less than 1.00 D can enhance near vision without significant loss of distance visual acuity or visual quality.
  • Monovision may reduce contrast sensitivity, stereopsis, and depth perception if anisometropia exceeds tolerance, potentially causing discomfort.

Guideline-Based Recommendations

Diagnosis

  • Comprehensive preoperative assessment including uncorrected distance visual acuity (UDVA), intraocular pressure, objective refraction, slit-lamp biomicroscopy, fundus examination, optical biometry, corneal topography, and visual quality assessment.
  • Determine ocular dominance using Mile’s test to guide mini-monovision design.

Management

  • Bilateral cataract phacoemulsification with implantation of Vivity EDOF IOLs.
  • Apply mini-monovision strategy by targeting emmetropia in dominant eye and near addition power of 0.5 to <1.0 D in non-dominant eye to enhance near vision.
  • Use standardized surgical technique and postoperative anti-inflammatory and anti-infective eye drops.

Monitoring & Follow-up

  • Postoperative follow-up at 1 day, 1 week, and 1 month to assess uncorrected distance, intermediate, and near visual acuity.
  • Objective visual quality measurements including modulation transfer function (MTF) and Strehl ratio (SR) at 1 month postoperatively.

Risks

  • Potential reduction in contrast sensitivity, stereopsis, and depth perception with monovision if anisometropia exceeds 1.00 D.
  • Patient discomfort such as asthenopia, dizziness, and headache related to anisometropia.
  • Exclude patients with concurrent ocular pathologies or history of ocular surgeries to minimize complications.

Patient & Prescribing Data

Adults undergoing bilateral cataract surgery with Vivity EDOF IOL implantation, stratified by visual preference and ocular dominance.

Mini-monovision with anisometropia between 0.5 and <1.0 D in non-dominant eye improves near vision and spectacle independence without clinically meaningful decline in distance vision or visual quality.

Clinical Best Practices

  • Careful patient selection excluding those with ocular comorbidities or prior ocular surgeries.
  • Preoperative determination of ocular dominance to guide refractive target setting.
  • Maintain anisometropia below 1.00 D to balance near vision improvement and minimize adverse effects on binocular vision.
  • Standardized surgical technique and postoperative care to optimize outcomes.
  • Comprehensive postoperative visual acuity and quality assessments to monitor efficacy and patient satisfaction.

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