SAPHO syndrome with membranous nephropathy and analgesic-induced nephropathy: a case report - Scorecard - MDSpire

SAPHO syndrome with membranous nephropathy and analgesic-induced nephropathy: a case report

  • By

  • Yuxin Qiao

  • Zuo Wang

  • Guohua Li

  • Duo Zhang

  • June 2, 2026

  • 0 min

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Clinical Scorecard: A Case Study of SAPHO Syndrome Associated with Membranous Nephropathy and Analgesic-Induced Kidney Injury

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationPrimarily women aged 30–50 years, but also includes men as evidenced by the case study.
Care Setting

Key Highlights

  • Treatment included intravenous cefuroxime sodium, methylprednisolone, and oral mycophenolate mofetil, leading to symptom resolution.

Guideline-Based Recommendations

Diagnosis

    Management

    • Standardized treatment with mannitol, sodium aescinate, and corticosteroids, along with supportive care and monitoring.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Intravenous cefuroxime sodium, methylprednisolone, and oral mycophenolate mofetil were used, targeting both infection and inflammation.

        Clinical Best Practices

        • Monitor renal function in patients with SAPHO syndrome showing signs of nephropathy, and consider differential diagnosis with IgA nephropathy, lupus nephritis, and other inflammatory disorders.

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          Original Source(s)

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