Multimodal neuroimaging protocol to explore the neural mechanisms of Tiao Shen Li Yan acupuncture in post-stroke dysphagia: a randomized sham-controlled clinical trial - Scorecard - MDSpire

Multimodal neuroimaging protocol to explore the neural mechanisms of Tiao Shen Li Yan acupuncture in post-stroke dysphagia: a randomized sham-controlled clinical trial

  • By

  • Jing Luo

  • Yan Huang

  • Lijun Wang

  • Guogao Zhang

  • Shaoyang Cui

  • Wenke Tang

  • Xueping Ding

  • Xueying Zhao

  • Yiqin Huang

  • Zhenhua Xu

  • Zhentao Zuo

  • June 19, 2026

  • 0 min

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Clinical Scorecard: Investigating the Neural Mechanisms of Tiao Shen Li Yan Acupuncture for Post-Stroke Dysphagia: A Randomized Sham-Controlled Neuroimaging Study

At a Glance

CategoryDetail
ConditionPost-Stroke Dysphagia
Key MechanismsAcupuncture-induced neuroplasticity and functional reorganization of brain networks.
Target PopulationPatients with post-stroke dysphagia.
Care SettingClinical trial setting.

Key Highlights

  • Acupuncture shows potential in improving swallowing function in post-stroke dysphagia.
  • Study employs multimodal neuroimaging techniques: resting-state fMRI and diffusion tensor imaging.
  • Trial includes both active and sham acupuncture groups for comparison.
  • Primary outcomes include functional and structural connectivity metrics.
  • Healthy volunteers will provide baseline neuroimaging reference data.

Guideline-Based Recommendations

Diagnosis

  • Standardized Swallowing Assessment (SSA) and videofluoroscopic swallowing study (VFSS) measures.

Management

  • Tiao Shen Li Yan acupuncture as a treatment modality for post-stroke dysphagia.

Monitoring & Follow-up

  • Assessment of swallowing function and quality of life through questionnaires.

Risks

  • Potential risks associated with acupuncture include minor discomfort or adverse reactions.

Patient & Prescribing Data

Patients diagnosed with post-stroke dysphagia.

Acupuncture may enhance swallowing function and promote neuroplastic changes.

Clinical Best Practices

  • Incorporate multimodal neuroimaging to evaluate treatment efficacy.
  • Utilize sham-controlled designs to assess true treatment effects.
  • Monitor both functional and structural changes in brain networks.

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