Comprehensive Care for People Who Use Drugs: Combining Infectious Diseases Services, Harm Reduction, and Primary Care - Scorecard - MDSpire

Comprehensive Care for People Who Use Drugs: Combining Infectious Diseases Services, Harm Reduction, and Primary Care

  • By

  • Ryan D Knodle

  • Sarah E Messmer

  • Albert L Murphy

  • Renata O Smith

  • Michael Huyck

  • Karen Cotler

  • Antonio D Jimenez

  • Stockton M Mayer

  • April 16, 2025

  • 0 min

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Clinical Scorecard: Integrated Healthcare Approaches for Individuals Who Use Drugs: Merging Infectious Disease Management, Harm Reduction Strategies, and Primary Care Services

At a Glance

CategoryDetail
ConditionHealth complications and infectious diseases among people who use drugs (PWUD), including substance use disorder (SUD), HIV, hepatitis C, and injection-related infections
Key MechanismsColocation of primary care, infectious diseases consultation, and harm reduction services within community-based programs trusted by PWUD
Target PopulationPeople who use drugs (PWUD), especially those with substance use disorder and injection drug use
Care SettingCommunity-based harm reduction programs and syringe service programs (SSPs) with embedded clinical services

Key Highlights

  • PWUD face increased risk of infectious diseases and low uptake of primary care due to stigma and logistical barriers.
  • Community-based harm reduction programs serve as trusted access points for integrated primary care and infectious disease services.
  • Colocated services in Chicago’s COIP program resulted in high utilization of care addressing SUD, HIV, hepatitis C, and other infections.

Guideline-Based Recommendations

Diagnosis

  • Screen PWUD for infectious diseases including HIV, hepatitis C, and sexually transmitted infections within harm reduction settings.
  • Assess for substance use disorder and injection-related complications during clinical encounters.

Management

  • Provide integrated primary care and infectious disease treatment alongside harm reduction and substance use disorder services.
  • Utilize trusted community outreach workers with lived experience to facilitate referrals and engagement.
  • Address chronic medical and psychiatric comorbidities common in PWUD.

Monitoring & Follow-up

  • Track clinical encounters and service utilization to assess engagement and health outcomes among PWUD.
  • Monitor infectious disease treatment adherence and response within colocated care models.

Risks

  • Recognize barriers such as stigma, homelessness, fear of child custody loss, and comorbid health issues that impede care access.
  • Be aware of high overdose mortality risk, especially opioid-related deaths, in the target population.

Patient & Prescribing Data

552 unique patients who use drugs, predominantly male, median age 43, mostly publicly insured

Majority of clinical encounters (71.3%) addressed active substance use disorder; 20% of encounters involved hepatitis C and HIV care, demonstrating feasibility of integrated service delivery in harm reduction settings.

Clinical Best Practices

  • Embed primary care and infectious disease providers within harm reduction programs to reduce barriers and stigma.
  • Employ outreach workers with lived substance use experience to build trust and improve service uptake.
  • Offer comprehensive care addressing infectious diseases, substance use disorder, and chronic medical conditions in a single accessible location.

References

Original Source(s)

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