Existing and emerging strategies for fertility preservation in female patients with leukemia
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By
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Amirhossein Abazarikia
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Amrita Purkayastha
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Wonmi So
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Mahsa Rasekhi
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So-Youn Kim
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June 1, 2026
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Clinical Scorecard: Current and Novel Approaches to Preserve Fertility in Female Leukemia Patients
At a Glance
| Category | Detail |
|---|
| Condition | |
| Key Mechanisms | Gonadotoxic effects of chemotherapy (e.g., alkylating agents) and radiotherapy leading to ovarian reserve depletion and primary ovarian insufficiency. |
| Target Population | |
| Care Setting | |
Key Highlights
- Implement fertility preservation discussions early in the treatment planning process.
Guideline-Based Recommendations
Diagnosis
Management
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Female patients with leukemia, particularly those undergoing gonadotoxic treatments.
Standard treatments include chemotherapy and hematopoietic stem cell transplantation, which are associated with significant fertility risks.
Clinical Best Practices
- multidisciplinary_collaboration
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