Advances in understanding the mitochondrial mechanisms underlying acupuncture therapy for post-stroke cognitive impairment - Scorecard - MDSpire

Advances in understanding the mitochondrial mechanisms underlying acupuncture therapy for post-stroke cognitive impairment

  • By

  • Xiao Luo

  • Yuting Dong

  • Ziqi Chen

  • Yijing Jiang

  • Tao Chen

  • Liu Wu

  • Cheng Xie

  • Qinjian Dong

  • Xin Mu

  • Juan Li

  • Rongjiang Jin

  • May 8, 2026

  • 0 min

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Clinical Scorecard: New Insights into Mitochondrial Mechanisms of Acupuncture in Treating Cognitive Impairment After Stroke

At a Glance

CategoryDetail
Condition
Key MechanismsMitochondrial dysfunction, oxidative stress, energy metabolism abnormalities, neuroinflammation, apoptosis, and mitochondrial quality control.
Target Population
Care Setting

Key Highlights

  • Acupuncture may regulate mitochondrial functions to alleviate PSCI.
  • Mitochondrial impairment is a leading trigger in post-stroke pathology.
  • Acupuncture shows potential in restoring mitochondrial ultrastructural integrity.
  • High-quality clinical evidence on acupuncture's efficacy in PSCI is limited; further studies are essential.
  • Future studies are needed to optimize treatment protocols and combination therapies.

Guideline-Based Recommendations

Diagnosis

    Management

      Monitoring & Follow-up

      • Evaluate cognitive performance and mitochondrial function regularly, including specific biomarkers.

      Risks

        Patient & Prescribing Data

        Acupuncture may enhance cognitive performance by modulating mitochondrial pathways, including improving energy metabolism and reducing oxidative stress.

        Clinical Best Practices

        • Incorporate mitochondrial function assessment in PSCI management.
        • Utilize acupuncture as part of a multidisciplinary approach to PSCI, involving neurologists, physiotherapists, and occupational therapists.

        References

        Original Source(s)

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