Case Report: Delirium and complications resulting from the abuse of compound liquorice tablets
By
Xiwen Tian
Liu Liu
Liyao Huang
Jubo Yin
Yanjuan Zeng
Yao Chen
Shanghao Yang
Xuhui Zhou
July 6, 2026
Clinical Scorecard: Case Study: Delirium and Adverse Effects Associated with the Misuse of Compound Liquorice Tablets
At a Glance
Category Detail
Condition Substance Use Disorder due to Compound Liquorice Tablets Key Mechanisms Opioid dependence and withdrawal symptoms Target Population Individuals using compound liquorice tablets for cough relief Care Setting Addiction Medicine Center
Key Highlights
Patient developed delirium after discontinuing compound liquorice tablets. Withdrawal symptoms included confusion, hallucinations, and severe hypokalemia. Management included benzodiazepines, antidepressants, and antipsychotics. Successful withdrawal led to resolution of symptoms and stabilization. Emerging risk of abuse associated with compound liquorice tablets noted. Guideline-Based Recommendations
Diagnosis
ICD-10 criteria for opioid-induced mental and behavioral disorders. Management
Benzodiazepine tapering regimen for withdrawal symptoms. Use of antidepressants and antipsychotics for mood and psychotic symptoms. Monitoring & Follow-up
Active management of hypertension and correction of hypokalemia. Risks
Potential for addiction and severe adverse effects from misuse. Patient & Prescribing Data
29-year-old male with a history of COVID-19 and self-medication.
Gradual increase in dosage led to dependence and severe withdrawal symptoms.
Clinical Best Practices
Educate patients on the risks of misuse of compound liquorice tablets. Implement stricter prescription controls for medications with addiction potential. Conduct thorough assessments for patients presenting with altered mental status and substance use history. Related Resources & Content
