Testing Times for Immunohistochemistry
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By
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April Schrank-Hacker
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November 11, 2026
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7 min
Clinical Scorecard: Testing Times for Immunohistochemistry
At a Glance
| Category | Detail |
|---|---|
| Condition | IHC laboratory workflow capacity and operational bottlenecks |
| Key Mechanisms | The article identifies order intake, instrument loading, and unloading as workflow failure points. Paper- or batch-based intake, batching, inconsistent instrument interaction, and limited operating windows can delay starts and create instrument idle time; repeat stains re-enter constrained queues. |
| Target Population | Pathology laboratories performing IHC, including laboratories facing rising volumes, greater testing complexity, or staffing constraints. |
| Care Setting | Anatomic pathology and histology laboratory operations supporting IHC testing. |
Key Highlights
- The article identifies order intake, instrument loading, and unloading as IHC workflow failure points, according to workflow consultant David Newell.
- The article describes how delayed or batch-triggered intake and repeat stains can contribute to idle time and constrained queues.
- A reported example increased daily staining capacity from 120 to 180 slides by extending staining-area coverage from 8 to 9.5 hours and changing workflow, without adding equipment.
- The article describes end-to-end workflow review as a starting point for identifying bottlenecks and opportunities for improvement.
- The article states that a quality management system needs active monitoring and discussion, and that standardization can reduce variability and support more predictable outcomes.
Guideline-Based Recommendations
Diagnosis
- The article describes end-to-end workflow review as a starting point for identifying bottlenecks and opportunities for improvement.
Management
- Review order intake, instrument loading and unloading, batching practices, and operating windows, which the article identifies as workflow constraints.
- The article reports that workflow changes and longer staining-area coverage increased capacity in one example without new equipment.
Monitoring & Follow-up
- The article states that a robust quality management system needs to be actively monitored and discussed.
Risks
- The article describes IHC rework involving re-embedding or recutting, repeat staining, and pathologist re-review as extending turnaround times.
- The article identifies staffing constraints, fragmented ordering systems, batching, and limited operating windows as factors that constrain workflow.
- The article describes delays as creating pressure on downstream steps and laboratory teams.
Patient & Prescribing Data
Not specified; the article addresses laboratory operations rather than patient-level treatment.
No prescribing or treatment recommendations are provided. The article discusses IHC workflow and the timeliness of diagnostic reporting.
Clinical Best Practices
- Review the end-to-end IHC workflow to identify bottlenecks and opportunities for improvement.
- Examine order intake, instrument use, batching, and operating windows, which the article identifies as workflow factors affecting throughput.
- Actively monitor and discuss the quality management system, as stated in the article.
- The article describes standardization as reducing variability and supporting more predictable outcomes.
Related Resources & Content
Based on findings from:
Testing Times for Immunohistochemistry
April Schrank-Hacker. The Pathologist, 2026.
https://www.thepathologist.com/issues/2026/articles/november/testing-times-for-immunohistochemistry/
This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.