Clinical Scorecard: Video: Leading the Alpha Charge – with Øystein Soug
At a Glance
Category
Detail
Condition
Cancers that have spread to the abdominal cavity
Key Mechanisms
Radspherin is a receptor-independent alpha-emitting radiopharmaceutical delivered directly into the peritoneum, intended to concentrate radiation around residual cancer cells while limiting exposure elsewhere in the body.
Target Population
People with cancers that have spread to the abdominal cavity; the article does not specify eligibility criteria.
Care Setting
Radiopharmaceutical development and treatment involving direct intraperitoneal delivery; the article does not specify a clinical care setting.
Key Highlights
Oncoinvent is developing Radspherin for cancers that have spread to the abdominal cavity.
Radspherin uses receptor-independent alpha emission and is delivered directly into the peritoneum.
Øystein Soug discusses lessons from helping bring Xofigo to market.
Manufacturing and supply chains remain challenges for radiopharmaceuticals, according to Soug.
Soug discusses new isotopes, delivery methods, combination strategies, and Oslo’s emergence as a radiopharmaceutical hub.
Guideline-Based Recommendations
Diagnosis
Management
Monitoring & Follow-up
Risks
Patient & Prescribing Data
The therapy is being developed for cancers that have spread to the abdominal cavity; no prescribing or eligibility details are provided.
Radspherin is described as an investigational, receptor-independent alpha-emitting radiopharmaceutical delivered directly into the peritoneum. The article provides no dosing, safety, or efficacy data.
Piers Ingram discusses the resurgence of immunology, engineering-led drug discovery, and how artificial intelligence can shape the next generation of medicines