Assessing Bleeding Risk and Outcomes in Left Main Percutaneous Coronary Intervention: The Prognostic Role of the PRECISE-DAPT Score - Scorecard - MDSpire
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Assessing Bleeding Risk and Outcomes in Left Main Percutaneous Coronary Intervention: The Prognostic Role of the PRECISE-DAPT Score

  • By

  • En-Shao Liu

  • Yan-Ning Shih

  • Yi-Ting Wu

  • Haw-Ting Tai

  • Kuo-Ming Yang

  • Ta-Hsin Tai

  • Cheng-Hung Chiang

  • Feng-Yu Kuo

  • March 10, 2026

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Clinical Scorecard: Assessing Bleeding Risk and Outcomes in Left Main Percutaneous Coronary Intervention: The Prognostic Role of the PRECISE-DAPT Score

At a Glance

CategoryDetail
ConditionLeft Main Coronary Artery Disease
Key MechanismsIncreased myocardial territory at risk and potential for adverse cardiovascular outcomes.
Target PopulationPatients undergoing left main percutaneous coronary intervention (PCI).
Care SettingHigh-volume tertiary medical center.

Key Highlights

  • Dual antiplatelet therapy (DAPT) is critical post-PCI to reduce ischemic events.
  • The PRECISE-DAPT score estimates bleeding risk in PCI populations.
  • High bleeding risk (HBR) patients have worse clinical outcomes post-LM PCI.

Guideline-Based Recommendations

Diagnosis

  • Use the PRECISE-DAPT score to assess bleeding risk.

Management

  • Implement DAPT based on clinical presentation and physician judgment.

Monitoring & Follow-up

  • Monitor for major adverse cardiac and cerebrovascular events (MACCE) and bleeding outcomes.

Risks

  • Consider risks of prolonged DAPT, especially in patients with high bleeding risk.

Patient & Prescribing Data

Patients undergoing first left main PCI without prior CABG or STEMI.

DAPT regimen and duration should be tailored to individual patient risk profiles.

Clinical Best Practices

  • Conduct multidisciplinary Heart Team evaluations for complex cases.
  • Utilize standardized tools like the PRECISE-DAPT score for risk assessment.

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