Clinical Scorecard: Influence of Menstrual Cycle Stages on Postoperative Nausea and Vomiting in Premenopausal Women Following Laparoscopic Gastrointestinal Surgery: A Secondary Analysis of a Randomized Controlled Trial

At a Glance

Key Highlights

• No significant difference in PONV incidence between non-luteal and luteal phases during 0–24 h post-surgery.
• PONV incidence was 44.5% in non-luteal and 47.1% in luteal phase.
• Sensitivity analyses showed no significant association between surgery-to-ovulation interval and PONV outcomes.
• No significant differences in nausea, emetic episodes, or antiemetic medication use between groups.

Guideline-Based Recommendations

Diagnosis

• Assess PONV risk factors including sex, age, and history of motion sickness.

Management

• Consider antiemetic medications for high-risk patients.

Monitoring & Follow-up

• Monitor for PONV during the first 120 hours post-surgery.

Risks

• PONV can lead to dehydration, electrolyte imbalances, and delayed recovery.

Patient & Prescribing Data

Premenopausal women with regular menstrual cycles.

No specific treatment adjustments based on menstrual cycle phase were indicated.

Clinical Best Practices

• Utilize a comprehensive assessment of PONV risk factors preoperatively.
• Implement standardized protocols for antiemetic administration in high-risk patients.

Related Resources & Content

• Study Approval and Ethics