Knowledge, attitudes, and practices of patients with chronic kidney disease toward osteosarcopenia - Scorecard - MDSpire

Knowledge, attitudes, and practices of patients with chronic kidney disease toward osteosarcopenia

  • By

  • Chunmei Yang

  • Wei Wei

  • Wenhui Chai

  • Tao Li

  • Yue Ma

  • Xuan Wang

  • Mei Liu

  • Bumaryam Abla

  • Hongtao Cai

  • Ping Li

  • Ying Liu

  • Jiao Liu

  • March 12, 2026

  • 0 min

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Clinical Scorecard: Patient Awareness, Attitudes, and Practices Regarding Osteosarcopenia in Chronic Kidney Disease: A Cross-Sectional Study

At a Glance

CategoryDetail
ConditionOsteosarcopenia in Chronic Kidney Disease (CKD)
Key MechanismsProgressive loss of skeletal muscle mass and bone mineral density due to CKD-related metabolic disturbances, chronic inflammation, hormonal imbalances, and mineral metabolism alterations leading to increased fracture risk and physical decline.
Target PopulationPatients with chronic kidney disease (CKD) stages 1–5
Care SettingOutpatient and inpatient clinical settings managing CKD patients

Key Highlights

  • Patients with CKD demonstrated suboptimal knowledge (31.65%), attitudes (68.66%), and practices (55.78%) toward osteosarcopenia.
  • Knowledge positively influenced attitudes and practices, with attitudes also directly improving practices.
  • Factors such as social support, confidence in preventing osteosarcopenia, and functional status were independently associated with knowledge levels.

Guideline-Based Recommendations

Diagnosis

  • Recognize osteosarcopenia as a combined musculoskeletal complication in CKD requiring integrated assessment of muscle mass, strength, and bone density.
  • Use clinical and biochemical markers per CKD-MBD guidelines to identify bone disorders contributing to osteosarcopenia.

Management

  • Implement patient education programs to improve knowledge and self-management behaviors targeting muscle and bone health.
  • Promote physical activity, nutritional support, and fall prevention strategies tailored for CKD patients.
  • Address metabolic disturbances and hormonal imbalances contributing to osteosarcopenia.

Monitoring & Follow-up

  • Regularly assess muscle function and bone mineral density in CKD patients to detect early osteosarcopenia.
  • Monitor patient adherence to self-management practices and confidence levels in preventing osteosarcopenia.

Risks

  • Increased risk of falls and fractures due to combined muscle weakness and bone fragility.
  • Potential for worsened morbidity and mortality if osteosarcopenia is unrecognized and untreated.

Patient & Prescribing Data

585 CKD patients aged ≥18 years with varying functional statuses and social support levels

Improving patient knowledge and confidence in preventing osteosarcopenia is associated with better attitudes and self-management practices, suggesting targeted education and support interventions are critical.

Clinical Best Practices

  • Assess patient knowledge, attitudes, and practices regarding osteosarcopenia to identify educational needs.
  • Incorporate multidisciplinary approaches addressing both muscle and bone health in CKD management.
  • Enhance social support and patient confidence to improve engagement in preventive behaviors.
  • Tailor interventions considering patient functional status and living conditions.

References

Original Source(s)

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