Fewer poor joint awareness results with cementless TKA compared with the same-design cemented implant - Scorecard - MDSpire
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Cementless TKA Is Associated With Fewer Poor Joint-Awareness Outcomes Than a Cemented Implant of the Same Design

  • By

  • Luca De Berardinis

  • Filippo Leggieri

  • Paolo Salari

  • Giuseppe Polizzotti

  • Andrea Baldini

  • October 9, 2026

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Clinical Scorecard: Cementless and Cemented Total Knee Arthroplasty: A Non-randomised Comparison of Joint-Awareness Outcomes

At a Glance

CategoryDetail
ConditionClinical topic addressed by the source article: Cementless TKA Is Associated With Fewer Poor Joint-Awareness Outcomes Than a Cemented Implant of the Same Design
Key MechanismsMechanisms or clinical associations described in the source article.
Target PopulationPopulation described in the source article.
Care SettingSingle-institution, non-randomised, two-cohort study of 109 consecutive primary TKAs performed from January 2021 through July 2022.

Key Highlights

  • The study compared 55 cemented and 54 cementless TKAs using the same implant design.
  • Cohort allocation was non-random and based on surgeon preference; younger patients were more often assigned cementless fixation.
  • The groups differed significantly in age, sex distribution, and BMI, while preoperative Oxford Knee Score and ASA classification did not differ significantly.
  • Outcomes assessed included the 24-month Forgotten Joint Score-12 and Oxford Knee Score, patient acceptable symptom state, and time to functional satisfaction.
  • The supplied article excerpt does not include study results, so comparative outcome findings cannot be reported.

Guideline-Based Recommendations

Diagnosis

  • Eligibility was assessed in patients undergoing primary TKA for end-stage bone-on-bone knee osteoarthritis.

Management

  • The study used either cemented or cementless fixation with the same implant design; fixation assignment was non-random and based on surgeon preference.
  • A fast-track rehabilitation protocol began a few hours after surgery and included full weight-bearing, walking, training, and isometric exercises.

Monitoring & Follow-up

  • Follow-up assessments were scheduled at 3 weeks, 6 weeks, 6 months, 12 months, and 24 months.
  • Radiographic follow-up used anteroposterior and lateral weight-bearing views to assess implant positioning, radiolucent lines, and evidence of loosening.
  • Oxford Knee Score was collected preoperatively and at 24 months; Forgotten Joint Score-12 was collected at 24 months.

Risks

  • Non-random cohort allocation produced significant baseline differences in age, sex distribution, and BMI.
  • Valgus deformity and bilateral surgery were exclusion criteria.

Patient & Prescribing Data

109 consecutive patients undergoing primary unilateral TKA for end-stage bone-on-bone knee osteoarthritis: 55 cemented and 54 cementless procedures.

The cementless femoral component was 3D-printed Ti6Al4V with a 70% porous bone-facing surface and 520-µm pores; the cemented femoral component was cobalt-chromium alloy. Both versions had the same articular geometry and titanium-niobium nitride coating on the articulating surface; both tibial components were titanium.

Clinical Best Practices

  • The study used one high-volume, fellowship-trained adult knee reconstruction surgeon for all procedures.
  • The surgical protocol included mechanical alignment and measured resection; patellar resurfacing was not performed.
  • The cementless group’s bone cuts were made with a 1.27-mm saw blade under saline irrigation to prevent thermal necrosis.
  • The reported perioperative protocol included intravenous tranexamic acid, cefazolin, and postoperative enoxaparin prophylaxis.

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