Percutaneous endoscopic interlaminar discectomy vs. percutaneous endoscopic transforaminal discectomy for L5/S1 lumbar disc herniation: a systematic review and meta-analysis of randomized controlled trials - Scorecard - MDSpire

Percutaneous endoscopic interlaminar discectomy vs. percutaneous endoscopic transforaminal discectomy for L5/S1 lumbar disc herniation: a systematic review and meta-analysis of randomized controlled trials

  • By

  • Huatao Chen

  • Cai Cheng

  • July 14, 2026

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Clinical Scorecard: A Systematic Review and Meta-Analysis of Randomized Trials Comparing Percutaneous Endoscopic Interlaminar Discectomy and Transforaminal Discectomy for L5/S1 Lumbar Disc Herniation

At a Glance

CategoryDetail
ConditionL5/S1 Lumbar Disc Herniation
Key MechanismsComparison of percutaneous endoscopic interlaminar discectomy (PEID) and transforaminal discectomy (PETD) for surgical outcomes.
Target PopulationAdults with single-level L5/S1 lumbar disc herniation.
Care SettingMinimally invasive surgical procedures.

Key Highlights

  • PEID associated with shorter operative time compared to PETD.
  • Fluoroscopy frequency favored PEID over PETD.
  • No significant difference in hospital stay between PEID and PETD.
  • VAS leg pain and ODI outcomes were comparable across both techniques.
  • Complications/adverse events did not differ significantly between approaches.

Guideline-Based Recommendations

Diagnosis

  • Diagnosis of L5/S1 lumbar disc herniation should be confirmed through clinical evaluation and imaging.

Management

  • Consider PEID for patients with anatomical constraints favoring the interlaminar approach.

Monitoring & Follow-up

  • Monitor postoperative pain relief and functional recovery.

Risks

  • Evaluate risks of complications associated with both PEID and PETD.

Patient & Prescribing Data

Adults with single-level L5/S1 lumbar disc herniation.

PEID may reduce operative time and fluoroscopy frequency.

Clinical Best Practices

  • Individualize procedure selection based on anatomical considerations.
  • Utilize randomized controlled trial evidence for decision-making.

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