Accidental intravitreal injection of a veterinary inactivated FMD vaccine resulting in noninfectious intraocular inflammation: a case report - Scorecard - MDSpire

Accidental intravitreal injection of a veterinary inactivated FMD vaccine resulting in noninfectious intraocular inflammation: a case report

  • By

  • Xin Zhang

  • Peipei Jia

  • Zheng Fan

  • Xiaolu Cao

  • Zhimin Chen

  • May 22, 2026

  • 0 min

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Clinical Scorecard: Unintentional Intravitreal Administration of a Veterinary Inactivated Foot-and-Mouth Disease Vaccine Leading to Noninfectious Intraocular Inflammation: A Case Study

At a Glance

CategoryDetail
Condition
Key MechanismsImmune inflammatory response triggered by components of the bivalent inactivated FMD vaccine.
Target Population
Care Setting

Key Highlights

  • Accidental injection of a veterinary vaccine led to severe intraocular inflammation.
  • Patient presented with symptoms including redness and blurred vision after injection.
  • Diagnostic imaging revealed intraocular foreign body and significant retinal changes.
  • Surgical intervention included vitrectomy and removal of the injected material.

Guideline-Based Recommendations

Diagnosis

  • Evaluate for penetrating eye injury and intraocular foreign body.
  • Utilize imaging techniques such as B-scan ultrasonography and angiography.

Management

  • Initiate topical antibiotics and intraocular pressure-lowering therapies.
  • Consider surgical intervention if no improvement is observed.

Monitoring & Follow-up

  • Regular follow-up to assess visual acuity and intraocular pressure.
  • Monitor for signs of infection or further complications post-surgery.

Risks

  • Potential for irreversible vision loss due to intraocular inflammation.
  • Complications such as secondary glaucoma and retinal detachment.

Patient & Prescribing Data

Postoperative care includes antibiotics for infection prophylaxis.

Clinical Best Practices

  • Ensure strict adherence to guidelines prohibiting human use of veterinary vaccines.
  • Educate healthcare providers on the risks of accidental exposure to veterinary biological agents.

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