Epidemiology, determinants, and microbiological profile of implant-associated infections following intramedullary nailing in a tertiary hospital in Ethiopia - Scorecard - MDSpire
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Epidemiology, Risk Factors, and Microbial Characteristics of Infections After Intramedullary Nailing at a Tertiary Hospital in Ethiopia

  • By

  • Abebaw Muhabaw Zegeye

  • Suleiman Ayalew Belay

  • Ephrem Bekele Kebede

  • Birlew Teshome Alemayehu

  • Sileshi Serebe Zeleke

  • Yohannis Derbew Molla

  • October 14, 2026

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Clinical Scorecard: Epidemiology, Risk Factors, and Microbial Characteristics of Infections After Intramedullary Nailing at a Tertiary Hospital in Ethiopia

At a Glance

CategoryDetail
ConditionClinical topic addressed by the source article: Epidemiology, Risk Factors, and Microbial Characteristics of Infections After Intramedullary Nailing at a Tertiary Hospital in Ethiopia
Key MechanismsImplant-associated infection is described as a postoperative complication of intramedullary nailing; the supplied text does not specify its mechanisms.
Target PopulationPopulation described in the source article.
Care SettingCare setting described in the source article.

Key Highlights

  • The study aimed to quantify infection after intramedullary nailing, assess associated factors, and describe pathogens and antimicrobial resistance patterns.
  • The final analytic sample comprised 260 patients after exclusions for eligibility and incomplete registry data.
  • Infection was documented by the operating surgeon using criteria established by Metsemakers et al.
  • The hospital routinely administered perioperative antibiotic prophylaxis according to the Ethiopian Standard Treatment Guideline for General Hospitals.
  • The supplied article text does not include study findings or infection rates.

Guideline-Based Recommendations

Diagnosis

  • The study outcome was implant-associated infection documented by the operating surgeon according to Metsemakers et al. criteria.

Management

    Monitoring & Follow-up

    • The study recorded hospital-stay duration and patient, injury, and perioperative variables.

    Risks

    • The introduction cites prior studies linking high-grade open fractures, surgery delayed beyond 24 hours, tobacco use, diabetes mellitus, extended operative duration, and failure to administer prophylactic antibiotics with greater infection risk; these are not reported as findings of this study.

    Patient & Prescribing Data

    Eligible patients underwent intramedullary nailing for tibial or femoral fractures at the study hospital during 2021–2023; patients referred after nailing elsewhere and those with pathological fractures were excluded.

    Perioperative prophylaxis followed the hospital's Ethiopian Standard Treatment Guideline protocol, with regimens varying by fracture type and Gustilo–Anderson grade.

    Clinical Best Practices

    • The study recorded injury, clinical presentation, and perioperative management characteristics alongside infection occurrence.

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