A Ten-Year Analysis of Receptor Variability and Phenotypic Changes in Metastatic Breast Cancer: Insights from a Retrospective Study of 363 Cases at a Single Institution - Scorecard - MDSpire
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A Ten-Year Analysis of Receptor Variability and Phenotypic Changes in Metastatic Breast Cancer: Insights from a Retrospective Study of 363 Cases at a Single Institution
Clinical Scorecard: A Ten-Year Analysis of Receptor Variability and Phenotypic Changes in Metastatic Breast Cancer: Insights from a Retrospective Study of 363 Cases at a Single Institution
At a Glance
Category
Detail
Condition
Key Mechanisms
Target Population
Women with recurrent/metastatic breast cancer, specifically those with paired primary and metastatic lesions.
Care Setting
Key Highlights
loss_of_HR_or_HER2_expression
Guideline-Based Recommendations
Diagnosis
Reassess hormone receptors in metastatic lesions when feasible, as per NCCN and ASCO guidelines.
Management
Monitoring & Follow-up
Risks
Patient & Prescribing Data
Include specific therapies that have shown improved outcomes with sustained or acquired HR/HER2 positivity.
