Assessing Temporal Changes in Retinal Non-Perfusion Using Ultra-Widefield Fluorescein Angiography After Intravitreal Therapy for Diabetic Retinopathy - Scorecard - MDSpire

Assessing Temporal Changes in Retinal Non-Perfusion Using Ultra-Widefield Fluorescein Angiography After Intravitreal Therapy for Diabetic Retinopathy

  • By

  • Callie Deng

  • Karthik Reddy

  • Yue Liang

  • Nikhil Bommakanti

  • Julie Rosenthal

  • Yannis M. Paulus

  • March 9, 2026

  • 0 min

Share

Clinical Scorecard: Assessing Temporal Changes in Retinal Non-Perfusion Using Ultra-Widefield Fluorescein Angiography After Intravitreal Therapy for Diabetic Retinopathy

At a Glance

CategoryDetail
Condition
Key Mechanisms
Target PopulationPatients aged 18 years or older with type 1 or 2 diabetes mellitus, including those with varying stages of diabetic retinopathy.
Care Setting

Key Highlights

  • Ultra-widefield fluorescein angiography captures 82% of the retinal surface area, improving detection of peripheral lesions.

Guideline-Based Recommendations

Diagnosis

    Management

    • First-line treatment for center-involving diabetic macular edema includes intravitreal anti-VEGF agents.
    • Consider individualized treatment plans based on the stage of diabetic retinopathy.

    Monitoring & Follow-up

      Risks

        Patient & Prescribing Data

        Fixed dosing of anti-VEGF may be necessary to sustain improvements in DR severity; monitor for side effects such as intraocular pressure changes.

        Clinical Best Practices

        • Employ UWF FA for comprehensive assessment of peripheral retinal areas.
        • Consider combination therapy with anti-VEGF and pan-retinal photocoagulation for PDR.
        • Educate patients on treatment options and expected outcomes.

        References

        Original Source(s)

        Related Content