Cumin anaphylaxis and allergy to spices in pediatrics: a case report and literature review - Scorecard - MDSpire

Cumin anaphylaxis and allergy to spices in pediatrics: a case report and literature review

  • By

  • Benedetta Pessina

  • Enrico Masiello

  • Mattia Giovannini

  • Maria Chiara Bardasi

  • Simona Barni

  • Francesco Catamerò

  • Angela Klain

  • Giulia Liccioli

  • Michele Miraglia Del Giudice

  • Elio Novembre

  • Lucrezia Sarti

  • Leonardo Tomei

  • Claudia Valleriani

  • Francesca Mori

  • July 6, 2026

  • 0 min

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Clinical Scorecard: Anaphylactic Reactions to Cumin and Pediatric Spice Allergies: A Case Study and Review of Existing Literature

At a Glance

CategoryDetail
ConditionSpice Allergy
Key MechanismsIgE-mediated and non-IgE-mediated mechanisms
Target PopulationPediatric patients
Care SettingAllergy Unit in a pediatric hospital

Key Highlights

  • First report of cumin anaphylaxis via inhalation in a pediatric patient.
  • Spice allergies account for 2-4% of all food allergies in adults.
  • Anaphylaxis to spices is documented as isolated case reports in children.
  • Prick-by-prick tests with spice powders are recommended for diagnosis.
  • Limited data on the reliability of skin tests with native spices.

Guideline-Based Recommendations

Diagnosis

  • Suspect spice allergies in patients with allergic manifestations after exposure to multiple foods.
  • Use prick-by-prick tests with spice powders as part of the diagnostic workup.

Management

  • Avoidance of identified allergens and use of prescribed medications for allergic reactions.

Monitoring & Follow-up

  • Monitor for allergic reactions following exposure to spices.

Risks

  • Inaccurate labeling of spices in food products may lead to unintentional exposure.

Patient & Prescribing Data

Pediatric patients with suspected spice allergies.

Inhaled corticosteroid-formoterol therapy may be used for respiratory symptoms.

Clinical Best Practices

  • Conduct thorough patient history and allergy testing for suspected spice allergies.
  • Educate families about potential allergens in pre-packaged foods.

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