Analysis of the trajectory of depressive symptoms and influencing factors in patients undergoing metabolic and bariatric surgery - Scorecard - MDSpire

Analysis of the trajectory of depressive symptoms and influencing factors in patients undergoing metabolic and bariatric surgery

  • By

  • Jia-li Zhang

  • Yi Zhu

  • Yan Shao

  • Jing Wang

  • Cheng-yan Pu

  • Xiao-yi Yang

  • Ya-jing Xu

  • Yi Shen

  • June 10, 2026

  • 0 min

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Clinical Scorecard: Examining the Progression of Depressive Symptoms and Contributing Factors in Obese Patients Post-Metabolic and Bariatric Surgery

At a Glance

CategoryDetail
ConditionDepressive symptoms in obese patients pre- and post-MBS
Key MechanismsAnxiety as a risk factor; medication adherence, vitality, role emotional, and resting potential as protective factors
Target PopulationObese patients undergoing metabolic and bariatric surgery
Care SettingChangzhou Second People’s Hospital

Key Highlights

  • Depressive scores significantly decreased at 1, 3, and 6 months postoperatively, indicating effective emotional management.
  • Anxiety is a consistent risk factor for depression in MBS patients, necessitating targeted interventions.
  • Higher medication adherence and vitality scores protect against depression progression, highlighting the need for support.
  • Two subgroups identified: mild depression decline and significant depression decline, with different management needs.
  • Postoperative follow-up is crucial for effective emotional management and tailored support strategies.

Guideline-Based Recommendations

Diagnosis

  • Use the 9-item patient health questionnaire to assess depressive symptoms.

Management

  • Monitor anxiety levels and medication adherence in MBS patients, and implement specific interventions for anxiety and depression.

Monitoring & Follow-up

  • Conduct perioperative and postoperative follow-ups on depressive emotions and monitor micronutrient levels.

Risks

  • Patients with comorbid anxiety and low medication adherence are at higher risk for severe depression.

Patient & Prescribing Data

184 obese patients undergoing MBS

Postoperative depression levels decreased significantly, highlighting the need for tailored emotional support strategies.

Clinical Best Practices

  • Identify and address anxiety in obese patients prior to MBS.
  • Encourage high medication adherence and monitor vitamin B12 and other micronutrient levels.

Related Resources & Content

Original Source(s)

Analysis of the trajectory of depressive symptoms and influencing factors in patients undergoing metabolic and bariatric surgery

  • by Jia-li Zhang, Yi Zhu, Yan Shao, Jing Wang, Cheng-yan Pu, Xiao-yi Yang, Ya-jing Xu, Yi Shen

  • June 10, 2026

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