Case report : Early-Onset Juvenile Psoriatic Arthritis Presenting at 15 Months: A Diagnostic Challenge in Infancy
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By
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Atawneh, Mayar
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Hasasna, Lana
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Atyani, Moath
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Alami, Mohammad
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Abunejma, Fawzy M.
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April 29, 2026
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Clinical Scorecard: Case Study: Diagnosing Early-Onset Juvenile Psoriatic Arthritis in a 15-Month-Old: Challenges in Infant Presentation
At a Glance
| Category | Detail |
|---|
| Condition | |
| Key Mechanisms | Guttate psoriatic lesions followed by knee arthritis; inflammatory process indicated by elevated CRP and ESR. |
| Target Population | |
| Care Setting | |
Key Highlights
- Rare presentation of JPsA in a 15-month-old.
- Diagnosis confirmed by ultrasound and ILAR criteria.
- Negative autoimmune serology with positive inflammatory markers.
Guideline-Based Recommendations
Diagnosis
- Follow ILAR criteria for Juvenile Psoriatic Arthritis.
Management
Monitoring & Follow-up
- Monitor inflammatory markers such as CRP and ESR.
Risks
- Potential for misdiagnosis due to atypical presentation.
Patient & Prescribing Data
Infants and toddlers with early-onset JPsA.
Clinical Best Practices
- Utilize imaging to confirm synovitis in ambiguous cases.
- Consider family history of autoimmune diseases in diagnosis.
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