The Evolution of Canaloplasty
Explore the latest in glaucoma surgery as innovative canaloplasty techniques enhance Schlemm's canal function and improve patient outcomes.
By
John S. McInnes, MD, JD
Nathan M. Radcliffe, MD
Cynthia Mattox, MD
John S. McInnes, MD, JD
Nathan M. Radcliffe, MD
Cynthia Mattox, MD
John S. McInnes, MD, JD
Nathan M. Radcliffe, MD
Cynthia Mattox, MD
May 1, 2026
Clinical Scorecard: The Evolution of Canaloplasty
At a Glance
Category Detail
Condition Open-Angle Glaucoma Key Mechanisms Intraluminal dilation of Schlemm’s canal and placement of implantable bioscaffold to enhance aqueous outflow and lower intraocular pressure (IOP). Target Population Patients with open-angle glaucoma. Care Setting Ophthalmology surgical settings.
Key Highlights
Canaloplasty enhances Schlemm’s canal function through dilation and scaffolding. Ab interno techniques are emerging as less invasive alternatives to traditional methods. Canaloplasty shows greater IOP reduction compared to viscoelastic-only dilation. New implantable scaffolding materials are being developed for improved outcomes. CPT code 66175 is associated with canaloplasty procedures. Guideline-Based Recommendations
Diagnosis
Assess Schlemm’s canal diameter and function using imaging techniques. Management
Consider canaloplasty for patients with inadequate IOP control. Monitoring & Follow-up
Regularly monitor IOP and canal patency post-procedure. Risks
Potential complications include canal collapse and inadequate IOP reduction. Patient & Prescribing Data
Adults with open-angle glaucoma experiencing elevated IOP.
Canaloplasty may provide a durable solution for IOP management.
Clinical Best Practices
Utilize ab interno approaches to minimize invasiveness. Incorporate novel scaffolding materials for enhanced canal support. Follow established CPT coding for procedural documentation. References
