Case Report: A rare case of esophageal squamous cell carcinoma with metastases to the pancreas and stomach - Scorecard - MDSpire

Case Report: A rare case of esophageal squamous cell carcinoma with metastases to the pancreas and stomach

  • By

  • Yuhang Lv

  • Yanting Jiang

  • Kaiyuan Hui

  • Xiaodong Jiang

  • June 11, 2026

  • 0 min

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Clinical Scorecard: Uncommon Case of Esophageal Squamous Cell Carcinoma Metastasizing to the Pancreas and Stomach

At a Glance

CategoryDetail
ConditionEsophageal Squamous Cell Carcinoma (ESCC)
Key MechanismsAggressive malignancy with high propensity for local invasion and early dissemination.
Target PopulationPatients with a history of ESCC.
Care SettingOncology and surgical settings.

Key Highlights

  • Rare metastasis of ESCC to pancreas and stomach.
  • Patient underwent radical surgical resection after 37 months disease-free interval.
  • Postoperative treatment included immune checkpoint inhibitors and platinum-based chemotherapy.
  • Importance of considering rare metastases in differential diagnosis.
  • Aggressive surgical resection may be a viable treatment strategy.

Guideline-Based Recommendations

Diagnosis

  • Consider imaging studies for new pancreatic lesions in ESCC patients.

Management

  • Multidisciplinary approach including surgical resection and systemic therapy.

Monitoring & Follow-up

  • Regular imaging surveillance post-treatment for early detection of metastases.

Risks

  • Potential for distant metastasis even after prolonged disease-free intervals.

Patient & Prescribing Data

62-year-old male with a history of ESCC and significant comorbidities.

Combination of immune checkpoint inhibitors with platinum-based chemotherapy post-surgery.

Clinical Best Practices

  • Conduct thorough imaging for patients with ESCC presenting new abdominal symptoms.
  • Utilize a multidisciplinary team for treatment planning in complex cases.

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