Efficacy of different optical zone design with different myopia control for corneal refractive therapy (CRT): a one-year prospective cohort study - Scorecard - MDSpire

Efficacy of different optical zone design with different myopia control for corneal refractive therapy (CRT): a one-year prospective cohort study

  • By

  • Wei-Xia Lai

  • Meng-Tong Wang

  • Ren-Xiu Fu

  • Xixi Wu

  • Qiu-Ming Hu

  • Yi-Yue Jia

  • Yu-Yi Zhang

  • Dong-Yong Tang

  • Wei-Min Zhang

  • June 8, 2026

  • 0 min

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Clinical Scorecard: Effectiveness of Various Optical Zone Configurations in Myopia Management through Corneal Refractive Therapy: A One-Year Prospective Cohort Analysis

At a Glance

CategoryDetail
ConditionMyopia
Key MechanismsCorneal refractive therapy (CRT) lenses with inverse geometric design to slow myopia progression.
Target PopulationChildren aged 7–12 years with myopia (SER ranging from −0.50 D to −6.00 D).
Care SettingOptometry centres.

Key Highlights

  • 200 children enrolled in the study.
  • CRT lenses worn overnight to achieve clear vision and slow myopia progression.
  • Small optical zones (5 mm, 5.5 mm) are more effective in suppressing axial length elongation.
  • Participants followed a strict wearing schedule of at least 8 hours per night.
  • Comprehensive evaluations included naked vision, ocular surface assessment, and corneal topography.

Guideline-Based Recommendations

Diagnosis

  • Myopia diagnosis confirmed by mydriasis optometry.

Management

  • Use of CRT lenses tailored to individual corneal morphology and visual demands.

Monitoring & Follow-up

  • Follow-up visits at one day, one week, one month, and every three months thereafter.

Risks

  • Exclusion of children with prior myopia control measures or other eye diseases.

Patient & Prescribing Data

Children aged 7–12 years with myopia.

CRT lenses fitted according to standardized guidelines to optimize therapeutic outcomes.

Clinical Best Practices

  • Perform comprehensive evaluations based on age, initial myopic refractive error, and corneal topography.
  • Ensure adherence to prescribed wearing schedule for optimal results.

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